Vitamin D Receptor / VDR

vitamin D (1,25- dihydroxyvitamin D3) receptor

The vitamin D receptor, a NR1 Thyroid Hormone-Like Receptor, is activated by calcitriol, the active hormonal form of vitamin D. The activated receptor binds DNA at a specific vitamin D-responsive element and promotes transcription of vitamin D target genes such as osteocalcin, the most abundant noncollagenous protein in bone. The vitamin D receptor affects growth, bone formation, and female reproduction. For example, this receptor modulates the growth and differentiation of keratinocytes and mediates the beneficial effects of vitamin D on psoriatic skin. It also inhibits hormone secretion by and proliferation of parathyroid cells. The vitamin D receptor functions either as a homodimer or as a heterodimer of vitamin D and retinoid acid X receptor subunits. Inactivation of the receptor leads to hypocalcemia and Rickets-alopecia syndrome. Recently, the vitamin D receptor has been shown to function as a receptor for the secondary bile acid lithocholic acid (LCA), which is hepatotoxic and a potential enteric carcinogen. Activation of VDR by LCA or vitamin D induced expression in vivo of CYP3A, a cytochrome P450 enzyme that detoxifies LCA in the liver and intestine. An alternatively spliced vitamin D receptor that has an altered ligand-binding domain has been isolated from rats.

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Antibodies (73)

ELISA Kits (26)

Proteins (14)

Type

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Development Kit (1)

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Target

Vitamin D Receptor / VDR (113)

Reactivity

Human (73)

Mouse (41)

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Avian (5)

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Adherent Cell Cultures (2)

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IHC-plus™ Vitamin D Receptor / VDR Antibody (aa181-230) LS-B7259

(4.0) Rating

Antibody:

Vitamin D Receptor / VDR Rabbit anti-Human Polyclonal (aa181-230) Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$460

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Vitamin D Receptor / VDR Antibody (aa377-402) LS-C407668

(4.0) Rating

(1) Publication(s)

Antibody:

Vitamin D Receptor / VDR Rabbit anti-Human Polyclonal (aa377-402) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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IHC-plus™ Vitamin D Receptor / VDR Antibody (aa89-105) LS-B2577

(4.0) Rating

Antibody:

Vitamin D Receptor / VDR Rat anti-Chicken Monoclonal (aa89-105) Antibody

Reactivity:

Frog, Chicken, Mouse, Rat, Hamster, Pig, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

250 µl/$485

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IHC-plus™ Vitamin D Receptor / VDR Antibody (clone 2F4) LS-B4449

(4.0) Rating

Antibody:

Vitamin D Receptor / VDR Mouse anti-Human Monoclonal (2F4) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$440

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Vitamin D Receptor / VDR Antibody (aa274-299) LS-C160512

Antibody:

Vitamin D Receptor / VDR Rabbit anti-Human Polyclonal (aa274-299) Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

Unconjugated

Price:

400 µl/$393

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Human Vitamin D Receptor / VDR (Sandwich ELISA) ELISA Kit - LS-F5306

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$764

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Vitamin D Receptor / VDR Antibody (aa274-299, FITC) LS-C273292

Antibody:

Vitamin D Receptor / VDR Rabbit anti-Human Polyclonal (aa274-299) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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Vitamin D Receptor / VDR Antibody (aa274-299, PE) LS-C273294

Antibody:

Vitamin D Receptor / VDR Rabbit anti-Human Polyclonal (aa274-299) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

PE Conjugated

Price:

200 µl/$952

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Vitamin D Receptor / VDR Antibody (aa274-299, APC) LS-C273290

Antibody:

Vitamin D Receptor / VDR Rabbit anti-Human Polyclonal (aa274-299) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

APC Conjugated

Price:

200 µl/$952

• FITC
• PE
• APC

• FITC
• PE
• APC

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Vitamin D Receptor / VDR Antibody (phospho-Ser208) LS-C199727

Antibody:

Vitamin D Receptor / VDR Rabbit anti-Human Polyclonal (pSer208) Antibody

Reactivity:

Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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Vitamin D Receptor / VDR Antibody (aa196-235) LS-C352989

Antibody:

Vitamin D Receptor / VDR Rabbit anti-Human Polyclonal (aa196-235) Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$299

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Vitamin D Receptor / VDR Antibody LS-C747110

Antibody:

Vitamin D Receptor / VDR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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Human Phospho-Vitamin D Receptor / VDR (Ser208) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1444

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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Vitamin D Receptor / VDR Antibody (aa16-65) LS-C118330

Antibody:

Vitamin D Receptor / VDR Rabbit anti-Human Polyclonal (aa16-65) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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Vitamin D Receptor / VDR Antibody LS-C157347

Antibody:

Vitamin D Receptor / VDR Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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Vitamin D Receptor / VDR Antibody (aa108-157) LS-C134928

Antibody:

Vitamin D Receptor / VDR Rabbit anti-Human Polyclonal (aa108-157) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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Vitamin D Receptor / VDR Antibody (N-Terminus) LS-C80171

Antibody:

Vitamin D Receptor / VDR Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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Vitamin D Receptor / VDR Antibody LS-C747114

Antibody:

Vitamin D Receptor / VDR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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Vitamin D Receptor / VDR Antibody (p208) LS-C823570

Antibody:

Vitamin D Receptor / VDR Rabbit anti-Human Polyclonal (p208) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

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Vitamin D Receptor / VDR Antibody LS-C801554

Antibody:

Vitamin D Receptor / VDR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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Vitamin D Receptor / VDR Antibody LS-C417415

Antibody:

Vitamin D Receptor / VDR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$305; 100 µg/$357

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Vitamin D Receptor / VDR Antibody LS-C661544

Antibody:

Vitamin D Receptor / VDR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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Vitamin D Receptor / VDR Antibody LS-C489776

Antibody:

Vitamin D Receptor / VDR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, IHC-P

Format:

Unconjugated

Price:

100 µl/$412

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Vitamin D Receptor / VDR Antibody (150-230 aa) LS-C386640

Antibody:

Vitamin D Receptor / VDR Rabbit anti-Human Polyclonal (150-230 aa) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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Vitamin D Receptor / VDR Antibody (Asn204) LS-C176619

Antibody:

Vitamin D Receptor / VDR Rabbit anti-Human Polyclonal (Asn204) Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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