Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone VG-1] (IgG1) to Human VEGFA / VEGF
IHC - Paraffin, Western blot, ELISA
Rabbit Polyclonal to Human VEGFA / VEGF
Human VEGFA / VEGF
Human (tested or 100% immunogen sequence identity)
Specificity and Use
VEGFA / VEGF antibody was raised against a synthetic peptide from N-terminus of human VEGF.
Reacts with a 19-22 kD (reduced) protein. Vascular endothelial growth factor (VEGF) is a homodimeric, disulfide-linked glycoprotein involved in angiogenesis which promotes tumor progression and metastasis. This antibody reacts with 165, 189 and 121 amino acid splice variants of VEGF of human, to a lesser extent, mouse and rat.
VEGFA / VEGF is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis.