• Antibodies
  • All Antibodies
  • Primary Antibodies
  • Secondary Antibodies
  • IHC-plus Antibodies
  • Isotype Control Antibodies
  • ELISA and Assay Kits
  • All Kits
  • Assay Kits
  • Traditional ELISA Kits
  • Cell-Based ELISA Kits
  • DNA-Binding ELISA Kits
  • Phospho-Specific ELISA Kits
  • ELISA Development Kits
  • Chemiluminescent CLIA Kits
  • Proteins
  • All Proteins
  • Recombinant Proteins
  • Native Proteins
  • Over-expression Lysates
  • Cell and Tissue Lysates
  • Bio-active Proteins
  • Animal-free Proteins
  • Synthetic Peptides
  • Biochemicals
  • All Biochemicals

  • Immunohistochemistry
  • Immunohistochemistry Reagents
  • Comprehensive IHC Reports
  • Custom IHC Services
  • TCR Screening Services
  • IHC-plus Antibodies
  • Immunohistochemistry Services

  • Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

  • TCR Screening Services

  • Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Have a question?
  • Purchasing
  • Product Ordering Terms and Conditions
  • Holiday Schedule
  • About the LSBio Guarantee
  • About Reviews
  • Reference Material
  • About LSBio (LifeSpan BioSciences Inc.)
  • About Our 2-million Specimen Tissue Bank
  • About Our IHC Validation Process
  • About Our IHC-plus™ Immunohistochemistry Protocol
  • Protocols
  • Secure Logins
  • Login to Our Secure ShareFile Site
  • Login to Our IHC Database
Contact Us

2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)
How to Buy - Details about how to buy our products. - To submit a new order. - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues. - To request technical information requests about an LSBio product or its application. - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login ▾
Wish List
View Cart

Anti-VCP Antibody (clone 4G9) IHC-plus™ LS-B1912

Note: This antibody replaces LS-C40951
Catalog Size Price
LS-B1912-50 50 µg (0.5 mg/ml) Unavailable

Related Products

46 VCP Antibodies

Most Popular VCP Antibodies

Anti-VCP Antibody (clone 4G9) IHC-plus™ LS-B1912
Mouse Monoclonal [clone 4G9] (IgG1) to Human VCP
IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation
Immunohistochemistry Image
Anti-VCP Antibody (clone 4A8) IHC-plus™ LS-B6068
Mouse Monoclonal [clone 4A8] (IgG2a,k) to Human VCP
IHC - Paraffin, Western blot, ELISA
Immunohistochemistry Image
Anti-VCP Antibody (C-Terminus) LS-C287469
Rabbit Polyclonal (IgG) to Human VCP
Human, Mouse
IHC - Paraffin, Western blot, Immunoprecipitation
Immunohistochemistry Image
Anti-VCP Antibody (aa749-766) LS-C313248
Rabbit Polyclonal to Human VCP
Human, Monkey, Mouse, Rat, Bat, Bovine, Guinea pig, Horse, Pig, Rabbit, Sheep, Chicken, Xenopus, Zebrafish, Drosophila, Insect
IHC - Paraffin, IHC - Frozen, ICC, Western blot
Immunohistochemistry Image
Anti-VCP Antibody (C-Terminus, Biotin) LS-C466186
Rabbit Polyclonal to Human VCP
Human, Chimpanzee, Gibbon, Monkey, Mouse, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit
IHC - Paraffin, Western blot, Immunoprecipitation
Biotin Conjugated
Immunohistochemistry Image

100% Guaranteed Publications (3)
Mouse Monoclonal [clone 4G9] (IgG1) to Human VCP
IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation


Human VCP
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [4G9]
Affinity purified


  • IHC - Paraffin (5 µg/ml)
  • Immunofluorescence (1 - 4 µg/ml)
  • Western blot
  • Immunoprecipitation

Specificity and Use

VCP antibody was raised against recombinant human VCP.
Recombinant human valosin containing protein
Immunohistochemistry: LS-B1912 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1912 was determined to be 5 ug/ml.


Phosphate-buffered solution, pH 7.2, 0.09% sodium azide at 0.5 mg/ml. Sourced in TCS.
Store at 4°C. Do not freeze.
For research use only.

Publications (3)

Selenoprotein K binds multiprotein complexes and is involved in the regulation of endoplasmic reticulum homeostasis. Shchedrina VA, Everley RA, Zhang Y, Gygi SP, Hatfield DL, Gladyshev VN. The Journal of biological chemistry. 2011 286:42937-48. [PubMed:22016385] [PMC:PMC3234841]
Altered intracellular localization and valosin-containing protein (p97 VCP) interaction underlie ATP7A-related distal motor neuropathy. Yi L, Donsante A, Kennerson ML, Mercer JF, Garbern JY, Kaler SG. Human molecular genetics. 2012 21:1794-807. [PubMed:22210628] [PMC:PMC3313796]
Regulation of subtilase cytotoxin-induced cell death by an RNA-dependent protein kinase-like endoplasmic reticulum kinase-dependent proteasome pathway in HeLa cells. Yahiro K, Tsutsuki H, Ogura K, Nagasawa S, Moss J, Noda M. Infection and immunity. 2012 80:1803-14. [PubMed:22354021] [PMC:PMC3347452]

About VCP

P55072 NM_007126 NP_009057.1

VCP Antibody, 15S Mg(2+)-ATPase p97 subunit Antibody, ALS14 Antibody, TER ATPase Antibody, TERA Antibody, Valosin containing protein Antibody, Yeast Cdc48p homolog Antibody, Valosin-containing protein Antibody, IBMPFD Antibody, p97 Antibody

Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles which derive from part-rough, part-smooth transitional elements of the endoplasmic reticulum (tER). Vesicle budding from the tER is an ATP-dependent process.


Anti-VCP antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1912 concentration 5 ug/ml.


Overnight nocodazole treated Hela cells stained with purified mouse monoclonal antibody against p97/VCP (clone 4G9), followed by Cy3 conjugated goat anti-mouse IgG and DAPI

Western blot

Western blot
Western blot of extracts from HeLa cells (Lane 1), Jurkat cells (Lane 2), MCF7 cells (Lane 3), or mouse splenocytes (Lane 4), using anti-p97/VCP, clone 4G9

Requested From: 
Date Requested: 3/23/2018

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2018 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy

Catalog Number