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VCL / Vinculin

vinculin

Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.

Gene Name: vinculin
Family/Subfamily: Cytoskeleton
Synonyms: VCL, CMD1W, CMH15, Metavinculin, Vinculin, MVCL
Target Sequences: NM_014000 NP_054706.1 P18206

☰ Filters
Antibodies (105)
ELISA Kits (18)
Proteins (11)
Custom (4)
Over-Expression Lysate (2)
Primary (105)
Recombinant (9)
Sandwich (13)
Sandwich CLIA (1)
VCL / Vinculin (134)
Human (112)
Mouse (54)
Rat (47)
Bat (4)
Bovine (4)
Chicken (20)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Guinea pig (5)
Horse (4)
Monkey (5)
Pig (14)
Porcine (1)
Rabbit (11)
Sheep (2)
Xenopus (1)
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IHC (36)
IHC-Fr (6)
IHC-P (23)
WB (91)
Flo (4)
ELISA (24)
ICC (6)
IF (17)
IP (8)
Peptide-ELISA (5)
rabbit (75)
mouse (30)
Product Group
IHCPlus (8)
Ig (2)
IgG (30)
IgG1 (12)
IgG1,k (5)
IgG2b,k (2)
monoclonal mc (30)
polyclonal pc (75)
2C6-1B5 (1)
489220 (1)
7.00E+10 (1)
8B5 (1)
FB11 (2)
V284 (2)
VCL/2572 (2)
VCL/2573 (2)
VCL/2575 (2)
VIN-54 (4)
12 x 8-Well Microstrips (1)
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96-Well Strip Plate (16)
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Unconjugated (63)
aa1020-1134 (8)
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aa873-922 (4)
pTyr821 (4)
760-840 aa (2)
aa1016-1066 (2)
Internal (1)
aa 2-235 (1)
aa1012-1039 (1)
aa12-39 (1)
aa173-188 (1)
aa356-607 (1)
aa750-800 (1)
aa786-835 (1)
p821 (1)
pTyr100 (1)
pTyr1065 (1)
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VCL / Vinculin Antibody - Anti-Vinculin antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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VCL / Vinculin Rabbit anti-Human Polyclonal (aa786-835) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
VCL / Vinculin Antibody - Anti-Vinculin antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml. This image was taken for the unmodified form of this product. Other forms have not been tested.
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VCL / Vinculin Mouse anti-Human Monoclonal (Azide-free) Antibody
Human
IF, IHC, IHC-P, IP, WB
Unconjugated, Azide-free
50 µl/$485
VCL / Vinculin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
VCL / Vinculin Protein
Select
E. coli
His, N-Terminal
24.7 kDa
10 µg/$281; 50 µg/$442; 200 µg/$882; 1 mg/$1,989; 5 mg/$3,081; 2 mg/$2,176
VCL / Vinculin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$798
VCL / Vinculin Antibody - VCL / Vinculin antibody. IHC(P): Human Breast Cancer Tissue.
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VCL / Vinculin Rabbit anti-Human Polyclonal (aa173-188) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Rabbit, Mouse, Guinea pig, Sheep, Bovine, Bat, Rat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
VCL / Vinculin Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
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VCL / Vinculin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
VCL / Vinculin Antibody - Anti-VCL / Vinculin antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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VCL / Vinculin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
VCL / Vinculin Antibody - Immunohistochemical analysis of Vinculin staining in human heart formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP-conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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VCL / Vinculin Rabbit anti-Human Polyclonal (Internal) Antibody
Chicken, Rat, Pig, Mouse, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
VCL / Vinculin Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
VCL / Vinculin Rabbit anti-Human Polyclonal (aa1016-1066) Antibody
Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
Select
VCL / Vinculin Mouse anti-Human Monoclonal (V284) Antibody
Human
Flo, IF, IHC-Fr, IHC-P, IP, WB
Unconjugated
0.1 mg/$395
VCL / Vinculin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
VCL / Vinculin Antibody - Anti-Vinculin antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
VCL / Vinculin Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
VCL / Vinculin Antibody - Human Prostate, Smooth Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
VCL / Vinculin Rabbit anti-Human Polyclonal (aa356-607) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
Select
VCL / Vinculin Mouse anti-Human Monoclonal Antibody
Chicken, Rabbit, Mouse, Rat, Human
IHC, IHC-Fr, WB
Unconjugated
100 µg/$564
Select
VCL / Vinculin Rabbit anti-Human Polyclonal (pTyr1065) Antibody
Chicken, Mouse, Human
IP, WB
Unconjugated
10 Blots/$786
Select
VCL / Vinculin Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
VCL / Vinculin Mouse anti-Human Monoclonal (VIN-54) Antibody
Chicken, Mouse, Rat, Human
WB
Unconjugated
100 µg/$723
VCL / Vinculin Antibody - Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using Vinculin antibody at dilution of 1:200
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VCL / Vinculin Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µg/$351
VCL / Vinculin Antibody - Western Blot; Sample: Recombinant VCL, Human.
Select
VCL / Vinculin Mouse anti-Human Monoclonal Antibody
Rat, Pig, Human
WB
Unconjugated
100 µl/$322; 200 µl/$370; 500 µl/$529; 1 ml/$614
VCL / Vinculin Antibody - Western blot of VINC Antibody with human PANC1 Whole Cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
VCL / Vinculin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
VCL / Vinculin Antibody - 1:100 staining human heart muscle tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
VCL / Vinculin Rabbit anti-Human Polyclonal (pTyr821) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
VCL / Vinculin Antibody - Western blot of Vinculin phosphorylation expression in forskolin treated HeLa whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
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VCL / Vinculin Rabbit anti-Human Polyclonal (pTyr821) Antibody
Mouse, Rat, Human
ICC, IF, IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
VCL / Vinculin Antibody - Vinculin Antibody staining Vinculin in mouse skeletal muscle tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with formaldehyde and blocked with 3% BSA for 0. 5 hour at room temperature; antigen retrieval was by heat mediation with a citrate buffer (pH6). Samples were incubated with primary antibody (1/25) for 1 hours at 37°C. A undiluted biotinylated goat polyvalent antibody was used as the secondary antibody.
Select
VCL / Vinculin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, Flo, IHC-P, WB
Unconjugated
200 µl/$393
VCL / Vinculin Antibody - Western blot of Vinculin antibody
Select
VCL / Vinculin Rabbit anti-Human Polyclonal (760-840 aa) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Viewing 1-25 of 134 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).