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CD106 antibody LS-C5808 is a biotin-conjugated rat monoclonal antibody to mouse CD106 (VCAM1). Validated for Flow, Func, IF, IHC and IP.
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Review This ProductPopular VCAM1 / CD106 Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human, Monkey, Dog
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Species:
Human
Applications:
IHC, IHC - Frozen, Western blot, Flow Cytometry, ELISA
Species:
Human
Applications:
IHC, Western blot, Flow Cytometry, ELISA, Functional Assay
Species:
Mouse
Applications:
IHC, IHC - Frozen, Immunofluorescence, Immunoprecipitation, Flow Cytometry, Functional Assay
Product Description
CD106 antibody LS-C5808 is a biotin-conjugated rat monoclonal antibody to mouse CD106 (VCAM1). Validated for Flow, Func, IF, IHC and IP.
About VCAM1 / CD106
Vascular cell adhesion molecule 1, VCAM-1, is a surface glycoprotein expressed by cytokine-activated endothelium that mediates the adhesion of monocytes and lymphocytes. VCAM-1 and integrin alpha-4-beta-1 facilitate a critical cell-cell adhesion event required for survival of endothelial and mural cells during vascularization. Studies of heart development have shown that deficiencies of VCAM and in alpha-4 integrin also result in epicardial dissolution and subsequent myocardial thinning.
P19320
NM_001078
NP_001069.1
VCAM1 Antibody, CD106 Antibody, CD106 antigen Antibody, INCAM-100 Antibody, V-CAM 1 Antibody, VCAM-1 Antibody
Specifications
Target
Mouse VCAM1 / CD106
Host
Rat
Reactivity
Mouse
(tested or 100% immunogen sequence identity)
Clonality
IgG1,k
Monoclonal
[M/K-2]
Conjugations
Biotin
Purification
Purified
Modifications
Unmodified
Applications
- IHC
- Immunofluorescence
- Immunoprecipitation
- Flow Cytometry
- Functional Assay
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Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
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Specificity
Recognizes CD106/VCAM-1 (~Mr 100kD).
Usage
Identification and enumeration of CD106 cells by flow cytometry. Identification of VCAM-1+ cells by immunofluorescence and immunohistochemical staining. Blockage of lymphocyte adhesion in Whitlock-Witte long-term bone marrow cultures. Inhibition of lymphopoiesis in Whitlock-Witte cultures. Immunoprecipitation. Flow Cytometry: 1 ug/1E6 cells. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, Sodium Azide
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
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