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Anti-VAV3 Antibody (aa566-590) LS-C11018

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Wt. Vol. Conc. Price
200 µg - - $515
Inquire for larger quantities

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Rabbit Polyclonal (IgG) to Mouse VAV3
Mouse, Rat
Western blot, Immunoprecipitation
Unconjugated

Details

Mouse VAV3
Rabbit
Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Protein A purified

Applications

Western blot, Immunoprecipitation

Specificity and Use

VAV3 antibody was raised against kLH-conjugated, synthetic peptide corresponding to aa566-590 (NSVEQGPFKPPEKRTNGLRRASRQV) of mouse Vav3. Percent identity by BLAST analysis: Mouse, Rat (100%); Pig (84%); Dog (80%).
aa566-590
Recognizes Vav3, Mr ~98kD. Species cross-reactivity: Mouse. Slight cross-reactivity to human.
Suitable for use in Western Blot and Immunoprecipitation. Western Blot Analysis: 0.5-2 ug/ml of this lot detected mouse Vav3 in Jurkat cells transfected with murine Vav3. The antibody has not been tested for its ability to detect endogenous levels of protein in WB at this time. Immunoprecipitation: Has been reported by an independent laboratory to immunoprecipitate Vav3 from primary mouse thymocytes and overexpressed myc-tagged murine Vav3 in Jurkat cell lysate.

Packaging

0.1 M Tris-glycine, pH 7.4, 0.15 M sodium chloride, 0.05% sodium azide, 30% glycerol.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About VAV3

Q9UKW4 NM_006113 NP_006104.4

VAV3 Antibody, VAV-3 Antibody, Vav 3 oncogene Antibody

Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity). May be important for integrin-mediated signaling, at least in some cell types.

Requested From: United States
Date Requested: 9/29/2016

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