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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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VAV1 / VAV Antibody (phospho‑Tyr174) LS‑C178004
VAV antibody LS-C178004 is an unconjugated rabbit polyclonal antibody to VAV (VAV1) from human, mouse and rat. Validated for WB.
Catalog
Size
Price
LS-C178004-100
100 µl
Unavailable

Popular VAV1 / VAV Products

Antibody
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Species: Human
Applications: IHC, IHC - Paraffin, Western blot

Product Description

VAV antibody LS-C178004 is an unconjugated rabbit polyclonal antibody to VAV (VAV1) from human, mouse and rat. Validated for WB.
About VAV1 / VAV
VAV1 / VAV is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. P15498 NM_005428 NP_005419.2

VAV1 Antibody, p95vav Antibody, VAV Antibody, Vav 1 oncogene Antibody, Proto-oncogene vav Antibody


Specifications

Target
Human VAV1 / VAV
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
Immunogen
VAV1 / VAV antibody was raised against synthetic phosphopeptide around pTyr174 of human VAV1 / VAV
Epitope
pTyr174
Specificity
Human VAV1 / VAV
Presentation
PBS, pH 7.2, 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western blot of p-Vav1 (Y174) pAb in extracts from Jurkat UV cells.
Western blot of p-Vav1 (Y174) pAb in extracts from Jurkat UV cells.

Western blot

Western blot of p-Vav1 (Y174) pAb in extracts from Jurkat UV cells.
Western blot of p-Vav1 (Y174) pAb in extracts from Jurkat UV cells.

Western blot

Western blot of p-Vav1 (Y174) pAb in extracts from Jurkat UV cells.
Western blot of p-Vav1 (Y174) pAb in extracts from Jurkat UV cells.

Western blot

Western blot of p-Vav1 (Y174) pAb in extracts from Jurkat UV cells.
Western blot of p-Vav1 (Y174) pAb in extracts from Jurkat UV cells.


Requested From: 
Date Requested: 6/24/2018

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