VAV1 / VAV

vav 1 guanine nucleotide exchange factor

VAV1 / VAV is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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Products

Antibodies (61)

Proteins (7)

ELISA Kits (3)

Type

Cell-Based (1)

Cell-Based Phosphorylation (1)

Over-Expression Lysate (2)

Primary (61)

Recombinant (5)

Sandwich (1)

Target

VAV1 / VAV (71)

Reactivity

Human (55)

Mouse (30)

Rat (24)

Chimpanzee (3)

Dog (2)

Horse (2)

Monkey (3)

Xenopus (2)

Application

IHC (11)

IHC-P (2)

WB (55)

Flo (3)

ELISA (18)

IF (5)

IP (2)

Peptide-ELISA (7)

Host

rabbit (57)

mouse (4)

Product Group

IHCPlus (1)

Isotype

IgG (30)

IgG1 (2)

IgG1,k (1)

IgG2b,k (1)

Clonality

monoclonal mc (4)

polyclonal pc (57)

Clone

1582CT802.383.58 (1)

2E+11 (2)

9C1 (1)

Format

96-Well Microplate (3)

APC (2)

APC Conjugated (3)

Azide-free (1)

Biotin Conjugated (4)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (3)

Unconjugated (39)

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Epitope

aa426-696 (8)

aa565-795 (8)

aa437-466 (7)

pTyr174 (7)

110-190 aa (4)

C-Terminus (4)

pTyr160 (3)

100-180 aa (2)

Ab-160 (1)

Ala168 (1)

Amino Acid: 121-324 (1)

Internal (1)

aa131-180 (1)

aa141-190 (1)

aa175-225 (1)

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Publications

No (71)

Sample Type

Adherent Cell Cultures (2)

Cell Lysates (1)

Tissue Homogenates (1)

Tag

GST, N-terminus (1)

His (1)

His-GST (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Mouse (1)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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VAV1 / VAV Antibody (aa131-180) LS-C117726

Antibody:

VAV1 / VAV Rabbit anti-Human Polyclonal (aa131-180) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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VAV1 / VAV Antibody (phospho-Tyr174) LS-C810063

Antibody:

VAV1 / VAV Rabbit anti-Human Polyclonal (pTyr174) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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Mouse/Human/Rat Phospho-VAV1 / VAV (Tyr174) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1109

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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VAV1 / VAV Antibody (clone 9C1) LS-C198421

Antibody:

VAV1 / VAV Mouse anti-Human Monoclonal (9C1) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$423

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VAV1 / VAV Antibody (Amino Acid: 121-324, clone 2E+11) LS-C759726

Antibody:

VAV1 / VAV Mouse anti-Human Monoclonal (Amino Acid: 121-324) (2E+11) Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

Unconjugated

Price:

100 µg/$503

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VAV1 / VAV Antibody (Ab-160) LS-C821963

Antibody:

VAV1 / VAV Rabbit anti-Human Polyclonal (Ab-160) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF

Format:

Unconjugated

Price:

100 µg/$357

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VAV1 / VAV Antibody LS-C808632

Antibody:

VAV1 / VAV Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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VAV1 / VAV Antibody (aa565-795, HRP) LS-C711211

Antibody:

VAV1 / VAV Rabbit anti-Mouse Polyclonal (aa565-795) (HRP) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639

Select

IHC-plus™ VAV1 / VAV Antibody (aa83-568) LS-B10777

(4.0) Rating

Antibody:

VAV1 / VAV Rabbit anti-Human Polyclonal (aa83-568) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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VAV1 / VAV Antibody (C-Terminus, Biotin) LS-C481777

Antibody:

VAV1 / VAV Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Human, Monkey, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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VAV1 / VAV Antibody (clone 2E+11) LS-C169104

Antibody:

VAV1 / VAV Mouse anti-Human Monoclonal (2E+11) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

Unconjugated

Price:

100 µl/$459

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VAV1 / VAV Antibody LS-C26414

Antibody:

VAV1 / VAV Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

ELISA, Flo, IP, WB

Format:

Unconjugated

Price:

100 µl/$688

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Human VAV1 / VAV Protein (Recombinant His-GST) (aa426-696) - LS-G24695

Source:

E. coli

Tag:

His-GST

Molecular Weight:

61.2 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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VAV1 / VAV Antibody (110-190 aa) LS-C380864

Antibody:

VAV1 / VAV Rabbit anti-Human Polyclonal (110-190 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

VAV1 / VAV Antibody (110-190 aa) LS-C386628

Antibody:

VAV1 / VAV Rabbit anti-Human Polyclonal (110-190 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

VAV1 / VAV Antibody (Ala168) LS-C176251

Antibody:

VAV1 / VAV Rabbit anti-Human Polyclonal (Ala168) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

VAV1 / VAV Antibody (100-180 aa) LS-C381559

Antibody:

VAV1 / VAV Rabbit anti-Human Polyclonal (100-180 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

VAV1 / VAV Antibody LS-C417433

Antibody:

VAV1 / VAV Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µg/$305; 100 µg/$357

Select

VAV1 / VAV Antibody (phospho-Tyr160) LS-C821962

Antibody:

VAV1 / VAV Rabbit anti-Human Polyclonal (pTyr160) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

100 µg/$357

Select

VAV1 / VAV Antibody (phospho-Tyr174) LS-C416560

Antibody:

VAV1 / VAV Rabbit anti-Human Polyclonal (pTyr174) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µg/$305; 100 µg/$357

Select

VAV1 / VAV Antibody (phospho-Tyr160) LS-C291160

Antibody:

VAV1 / VAV Rabbit anti-Human Polyclonal (pTyr160) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

VAV1 / VAV Antibody (110-190 aa) LS-C380865

Antibody:

VAV1 / VAV Rabbit anti-Human Polyclonal (110-190 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

VAV1 / VAV Antibody (aa437-466) LS-C326262

Antibody:

VAV1 / VAV Rabbit anti-Human Polyclonal (aa437-466) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

VAV1 / VAV Antibody (110-190 aa) LS-C386630

Antibody:

VAV1 / VAV Rabbit anti-Human Polyclonal (110-190 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

VAV1 / VAV Antibody (100-180 aa) LS-C386806

Antibody:

VAV1 / VAV Rabbit anti-Human Polyclonal (100-180 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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