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VANGL1 encodes a member of the tretraspanin family. The encoded protein may be involved in mediating intestinal trefoil factor induced wound healing in the intestinal mucosa. Mutations in this gene are associated with neural tube defects. Alternate splicing results in multiple transcript variants.
Gene Name: | VANGL planar cell polarity protein 1 |
Synonyms: | VANGL1, KITENIN, STB2, LPP2, STBM2, Van Gogh-like protein 1, Loop-tail protein 2 homolog, Strabismus 2, Vang-like protein 1 |
Target Sequences: | NM_138959 NP_620409.1 Q8TAA9 |
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