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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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UTS2 / Urotensin II Antibody LS‑C191372
Antibody
Urotensin II antibody LS-C191372 is an unconjugated rabbit polyclonal antibody to human Urotensin II (UTS2). Validated for ELISA.
Catalog
Size
Price
LS-C191372-200
200 µg (1 mg/ml)
Unavailable

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Product Description

Urotensin II antibody LS-C191372 is an unconjugated rabbit polyclonal antibody to human Urotensin II (UTS2). Validated for ELISA.
About UTS2 / Urotensin II
UTS2 / Urotensin II is a mature peptide that is an active cyclic heptapeptide absolutely conserved from lamprey to human. The active peptide acts as a vasoconstrictor and is expressed only in brain tissue. Despite the gene family name similarity, this gene is not homologous to urocortin, a member of the sauvagine/corticotropin-releasing factor/urotensin I family. Most of the proprotein is cleaved to make the mature peptide. O95399 NM_006786 NP_006777.1

UTS2 Antibody, Urotensin 2 Antibody, U-II Antibody, Urotensin II Antibody, PRO1068 Antibody, UII Antibody, Urotensin-2 Antibody


Specifications

Target
Human UTS2 / Urotensin II
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Applications
  • ELISA
Immunogen
Synthetic peptide corresponding to Glu-Thr-Pro-Asp-Cys-Phe-Trp- Lys-Tyr-Cys-Val (Disulfide Bridge: Cys5-Cys10) from human Urotensin II.
Specificity
Human Urotensin II. Shows 69% crossreactivity with rat Urotensin II and 10% with mouse Urotensin II. Does not crossreact with Endothelin-1 (human, porcine, rat, mouse, canine or bovine), CN-22 (human, porcine, rat), rat Adrenomedullin (aa1-50), ANF (rat, rabbit, mouse), Bradykinin, human Angiotensin II, rat BNP-45, rat BNP-32 or rat PAMP-20.
Usage
Radioimmunoassay: 0.24 ug/ml will bind ~30% in a system using human 125I-Urotensin II as a tracer.
Presentation
Lyophilized from PBS, pH 7.5
Reconstitution
200 µl Sterile distilled water
Storage
Lyophilized powder may be stored at -20°C. Stable for 1 year at -20°C. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Reconstituted product is stable for 1 year at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/21/2018

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