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Anti-USP6 / HRP1 Antibody (aa142-155) LS-C154898


Wt. Vol. Conc. Price
100 µg - 0.5 mg/ml Unavailable

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Goat Polyclonal to Human USP6 / HRP1


Human USP6 / HRP1
Human (tested or 100% immunogen sequence identity)
Immunoaffinity purified


ELISA (1:4000)

Specificity and Use

USP6 / HRP1 antibody was raised against synthetic peptide C-HHIDLDVRTTLRNH from an internal region (near N-terminus) of human USP6 (NP_004496.2). Percent identity by BLAST analysis: Human (100%); Chimpanzee, Gorilla (93%).
LS-E27881 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C154898. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Human USP6. This antibody is expected NOT to cross react to USP32 or to the TBC1D3 proteins.
Peptide ELISA: antibody detection limit dilution 1:4000. Western blot: Preliminary experiments in Human Testis, Prostate and Placenta lysates gave no specific signal but low background (at antibody concentration up to 1 ug/ml).


Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About USP6 / HRP1

P35125 NM_004505 NP_004496.2

USP6 Antibody, Proto-oncogene TRE-2 Antibody, Tre-2 Antibody, Tre-2 oncogene Antibody, Ubiquitin specific protease 6 Antibody, Ubiquitin thioesterase 6 Antibody, Deubiquitinating enzyme 6 Antibody, HRP1 Antibody, Hyperpolymorphic gene 1 Antibody, TBC1D3 and USP32 fusion Antibody, TRE2 Antibody, Ubiquitin thiolesterase 6 Antibody, USP6-short Antibody

Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.

Requested From: 
Date Requested: 3/28/2017

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