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USP4

ubiquitin specific peptidase 4 (proto-oncogene)

Hydrolase that deubiquitinates target proteins such as the receptor ADORA2A, PDPK1 and TRIM21. Deubiquitination of ADORA2A increases the amount of functional receptor at the cell surface. May regulate mRNA splicing through deubiquitination of the U4 spliceosomal protein PRPF3. This may prevent its recognition by the U5 component PRPF8 thereby destabilizing interactions within the U4/U6.U5 snRNP. May also play a role in the regulation of quality control in the ER.

Gene Name: ubiquitin specific peptidase 4 (proto-oncogene)
Family/Subfamily: Protease , Cysteine C19
Synonyms: USP4, Deubiquitinating enzyme 4, Unph, Ubiquitin thiolesterase 4, Ubiquitin thioesterase 4, Ubiquitin-specific protease 4, UNP
Target Sequences: NM_003363 NP_003354.2 Q13107

☰ Filters
Antibodies (43)
Proteins (5)
Over-Expression Lysate (2)
Primary (43)
Recombinant (3)
USP4 (48)
Human (42)
Mouse (5)
Rat (6)
Bat (1)
Bovine (2)
Chimpanzee (3)
Dog (2)
Guinea pig (3)
Horse (1)
Monkey (2)
Pig (2)
Rabbit (3)
IHC (25)
IHC-P (6)
WB (31)
ELISA (20)
IF (2)
IP (2)
Peptide-ELISA (1)
rabbit (41)
mouse (1)
goat (1)
Product Group
IHCPlus (3)
IgG (26)
IgG2a,k (1)
monoclonal mc (1)
polyclonal pc (42)
5E12 (1)
AP Conjugated (1)
APC Conjugated (3)
Azide-free (3)
Biotin Conjugated (6)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (3)
Unconjugated (18)
Internal (8)
C-Terminus (7)
aa1-30 (7)
aa903-933 (7)
N-Terminus (1)
aa2-14 (1)
aa225-275 (1)
aa313-362 (1)
aa925-C-term (1)
No (48)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
USP4 Antibody - Anti-USP4 / UNP antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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USP4 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µg/$460
USP4 Antibody - Anti-USP4 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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USP4 Rabbit anti-Human Polyclonal (Internal) Antibody
Rabbit, Dog, Bovine, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
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USP4 Rabbit anti-Human Polyclonal (aa925-C-term) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
USP4 Antibody - Immunohistochemistry image at a dilution of 1:500 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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USP4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
USP4 Antibody - Anti-USP4 / UNP antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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USP4 Rabbit anti-Human Polyclonal (Internal) Antibody
Rabbit, Dog, Bovine, Pig, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
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USP4 Rabbit anti-Human Polyclonal (aa903-933) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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USP4 Rabbit anti-Human Polyclonal (aa903-933) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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USP4 Rabbit anti-Human Polyclonal (aa903-933) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
USP4 Rabbit anti-Human Polyclonal (aa903-933) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
Select
USP4 Rabbit anti-Human Polyclonal (aa903-933) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
Select
USP4 Rabbit anti-Human Polyclonal (aa903-933) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
USP4 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
USP4 Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
USP4 Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
USP4 Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
Select
USP4 Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
Select
USP4 Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
USP4 Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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USP4 Rabbit anti-Human Polyclonal (aa903-933) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
USP4 Antibody - USP4 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human colon carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
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USP4 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
Select
USP4 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, IHC
Unconjugated
200 µl/$734
Select
USP4 Rabbit anti-Human Polyclonal (Internal) (Biotin) Antibody
Human
ELISA, IHC
Biotin Conjugated
200 µl/$952
Select
USP4 Rabbit anti-Human Polyclonal (Internal) (FITC) Antibody
Human
ELISA, IHC
FITC Conjugated
200 µl/$952
Select
USP4 Rabbit anti-Human Polyclonal (Internal) (APC) Antibody
Human
ELISA, IHC
APC Conjugated
200 µl/$952
USP4 Antibody - Western blot analysis of extracts of various cell lines, using USP4 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
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USP4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
USP4 Antibody - Western Blot analysis of USP4 expression in transfected 293T cell line by USP4 monoclonal antibody (M01), clone 5E12.Lane 1: USP4 transfected lysate (Predicted MW: 108.6 KDa).Lane 2: Non-transfected lysate.
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USP4 Mouse anti-Human Monoclonal (5E12) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
Viewing 1-25 of 48 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).