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Anti-USP4 Antibody (aa903-933) LS-C99534

Catalog Size Price
LS-C99534-400 400 µl Unavailable

Related Products

56 USP4 Antibodies

Most Popular USP4 Antibodies

Anti-USP4 Antibody (Internal) IHC-plus™ LS-A8564
Rabbit Polyclonal to Human USP4
Human, Monkey, Bovine, Dog, Pig, Rabbit
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-USP4 Antibody (Internal) IHC-plus™ LS-A8559
Rabbit Polyclonal to Human USP4
Human, Monkey, Bat, Bovine, Dog, Horse, Pig, Rabbit
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-USP4 Antibody (N-Terminus) IHC-plus™ LS-A8558
Rabbit Polyclonal to Human USP4
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-USP4 Antibody (C-Terminus) LS-C287680
Rabbit Polyclonal (IgG) to Human USP4
Human, Dog, Guinea pig, Horse, Pig, Rabbit
Western blot, Immunoprecipitation
Unconjugated
Anti-USP4 Antibody (C-Terminus) LS-C329043
Rabbit Polyclonal (IgG) to Human USP4
Human
IHC, Western blot, ELISA
Unconjugated

100% Guaranteed
Rabbit Polyclonal to Human USP4
Human
IHC - Paraffin, Western blot
Unconjugated

Details

Human USP4
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Ammonium sulfate precipitation
Unmodified

Applications

  • IHC - Paraffin (1:50 - 1:100)
  • Western blot (1:1000)

Specificity and Use

LS-E6880 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C99534. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa903-933
This USP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 903-933 amino acids from the C-terminal region of human USP4.

Packaging

PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About USP4

Q13107 NM_003363 NP_003354.2

USP4 Antibody, Deubiquitinating enzyme 4 Antibody, Unph Antibody, Ubiquitin thiolesterase 4 Antibody, Ubiquitin thioesterase 4 Antibody, Ubiquitin-specific protease 4 Antibody, UNP Antibody

Hydrolase that deubiquitinates target proteins such as the receptor ADORA2A, PDPK1 and TRIM21. Deubiquitination of ADORA2A increases the amount of functional receptor at the cell surface. May regulate mRNA splicing through deubiquitination of the U4 spliceosomal protein PRPF3. This may prevent its recognition by the U5 component PRPF8 thereby destabilizing interactions within the U4/U6.U5 snRNP. May also play a role in the regulation of quality control in the ER.

Immunohistochemistry

Immunohistochemistry
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Western blot

Western blot
The anti-USP4 C-term antibody is used in Western blot to detect USP4 in USP4-transfected HeLa cell lysate. Transfection data is kindly provided by Dr. B. Pierrat from the Novartis Institute for Biomedical Research (Basel, Switzerland).

Requested From: 
Date Requested: 6/24/2017

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