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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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USP3 / UBP Antibody (aa489‑519) LS‑C99532
UBP antibody LS-C99532 is an unconjugated rabbit polyclonal antibody to human UBP (USP3). Validated for IHC and WB.
Catalog
Size
Price
LS-C99532-400
400 µl
Unavailable

Popular USP3 / UBP Products

Anti-USP3 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1113 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bat, Dog
Applications: IHC, IHC - Paraffin, Western blot
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Species: Human
Applications: IHC, Immunofluorescence, Western blot, ELISA
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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Detection of Human USP3 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-USP3 used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.
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Antibody
Species: Human
Applications: IHC, Immunofluorescence, Western blot, ELISA

Product Description

UBP antibody LS-C99532 is an unconjugated rabbit polyclonal antibody to human UBP (USP3). Validated for IHC and WB.
About USP3 / UBP
Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required for proper progression through S phase and subsequent mitotic entry. May regulate the DNA damage response (DDR) checkpoint through deubiquitination of H2A at DNA damage sites. Associates with the chromatin. Q9Y6I4 NM_006537 NP_006528.2

USP3 Antibody, Deubiquitinating enzyme 3 Antibody, SIH003 Antibody, Ubiquitin specific protease 3 Antibody, UBP Antibody, Ubiquitin thiolesterase 3 Antibody, Ubiquitin thioesterase 3 Antibody, Ubiquitin specific peptidase 3 Antibody


Specifications

Target
Human USP3 / UBP
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Ammonium sulfate precipitation
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:50 - 1:100)
  • Western blot (1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Blocking Peptide
LS-E6879 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C99532. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa489-519
Specificity
This USP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 489-519 amino acids from the C-terminal region of human USP3.
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Western blot

Western blot of hUSP3-Y505 in K562, A375, NCI-H460 cell line lysates (35 ug/lane). USP3 (arrow) was detected using the purified antibody.
Western blot of hUSP3-Y505 in K562, A375, NCI-H460 cell line lysates (35 ug/lane). USP3 (arrow) was detected using the purified antibody.

Immunohistochemistry

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Western blot

Western blot of hUSP3-Y505 in K562, A375, NCI-H460 cell line lysates (35 ug/lane). USP3 (arrow) was detected using the purified antibody.
Western blot of hUSP3-Y505 in K562, A375, NCI-H460 cell line lysates (35 ug/lane). USP3 (arrow) was detected using the purified antibody.

Immunohistochemistry

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Western blot

Western blot of hUSP3-Y505 in K562, A375, NCI-H460 cell line lysates (35 ug/lane). USP3 (arrow) was detected using the purified antibody.
Western blot of hUSP3-Y505 in K562, A375, NCI-H460 cell line lysates (35 ug/lane). USP3 (arrow) was detected using the purified antibody.

Immunohistochemistry

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Western blot

Western blot of hUSP3-Y505 in K562, A375, NCI-H460 cell line lysates (35 ug/lane). USP3 (arrow) was detected using the purified antibody.
Western blot of hUSP3-Y505 in K562, A375, NCI-H460 cell line lysates (35 ug/lane). USP3 (arrow) was detected using the purified antibody.


Requested From: 
Date Requested: 6/21/2018

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