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USP19

ubiquitin specific peptidase 19

Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin-dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic-reticulum-associated degradation (ERAD) substrates. Regulates the stability of BIRC2/c-IAP1 and BIRC3/c-IAP2 by preventing their ubiquitination. Required for cells to mount an appropriate response to hypoxia and rescues HIF1A from degradation in a non-catalytic manner. Plays an important role in 17 beta-estradiol (E2)-inhibited myogenesis. Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis. Exhibits a preference towards 'Lys-63'-linked Ubiquitin chains.

Gene Name: ubiquitin specific peptidase 19
Family/Subfamily: Protease , Cysteine C19
Synonyms: USP19, KIAA0891, Ubiquitin thioesterase 19, Ubiquitin thiolesterase 19, Deubiquitinating enzyme 19, Ubiquitin specific protease 19, ZMYND9
Target Sequences: BC014934 BAA74914.1 O94966

☰ Filters
Antibodies (22)
Proteins (2)
Over-Expression Lysate (2)
Primary (22)
USP19 (24)
Human (20)
Mouse (6)
Rat (7)
Rabbit (1)
IHC (6)
IHC-P (4)
WB (18)
ELISA (9)
IF (1)
IP (3)
Peptide-ELISA (3)
SWB (1)
rabbit (21)
goat (1)
Product Group
IHCPlus (1)
PathPlus Cancer (2)
IgG (15)
polyclonal pc (22)
APC Conjugated (1)
Azide-free (2)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (17)
aa1289-1319 (7)
360-440 aa, Internal (1)
aa1-50 (1)
aa350-362 (1)
aa391-440 (1)
aa400-439 (1)
aa439-484 (1)
aa900-950 (1)
No (24)
Myc-DDK (Flag) (2)
Human (1)
293T Cells (1)
HEK 293 Cells (1)
USP19 Antibody - Anti-KIAA0891 / USP19 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
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USP19 Rabbit anti-Human Polyclonal (aa391-440) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
USP19 Antibody - Immunohistochemical analysis of USP19 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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USP19 Rabbit anti-Human Polyclonal (aa400-439) Antibody
Rabbit, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$299
USP19 Antibody - Western blot of USP19 antibody
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USP19 Rabbit anti-Human Polyclonal (360-440 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
USP19 Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer
Fast Shipping
USP19 Rabbit anti-Human Polyclonal Antibody
IHC-P, SWB
Unconjugated
50 µg/$460
USP19 Antibody - Staining NIH-3T3 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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USP19 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
USP19 Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer
Fast Shipping
USP19 Rabbit anti-Human Polyclonal Antibody
IHC-P
Unconjugated
50 µg/$460
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USP19 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
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USP19 Rabbit anti-Human Polyclonal (aa439-484) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$321; 100 µl/$403
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USP19 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$351
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USP19 Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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USP19 Rabbit anti-Human Polyclonal (aa900-950) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
Select
USP19 Rabbit anti-Human Polyclonal (aa1289-1319) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
USP19 Rabbit anti-Human Polyclonal (aa1289-1319) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
USP19 Rabbit anti-Human Polyclonal (aa1289-1319) (Azide-free) Antibody
Human
ELISA, WB
Unconjugated, Azide-free
200 µl/$734
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USP19 Rabbit anti-Human Polyclonal (aa1289-1319) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
USP19 Rabbit anti-Human Polyclonal (aa1289-1319) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
USP19 Rabbit anti-Human Polyclonal (aa1289-1319) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
USP19 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
USP19 Antibody - Western blot of hUSP19-L1304 in Jurkat cell line lysates (35 ug/lane). USP19 (arrow) was detected using the purified antibody.
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USP19 Rabbit anti-Human Polyclonal (aa1289-1319) Antibody
Human
WB
Unconjugated
400 µl/$393
USP19 Antibody - Detection of full length USP19 and its degradation fragments in mouse testis lysate (50ug) by Western blot using USP19polyclonal antibody.
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USP19 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$563
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USP19 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Human
IP
Unconjugated
10 µg/$295; 100 µl/$514
Select
USP19 Goat anti-Human Polyclonal (aa350-362) Antibody
Human
Peptide-ELISA
Unconjugated
100 µg/$401
USP19 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
145.5 kDa
20 µg/$215
USP19 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
145.5 kDa
100 µg/$710
Viewing 1-24 of 24 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).