USP17L2 / DUB3

ubiquitin specific peptidase 17-like family member 2

Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Regulates cell proliferation by deubiquitinating and inhibiting RCE1 thereby controlling the small GTPases NRAS and HRAS localization and activation. In parallel, mediates deubiquitination of CDC25A, preventing CDC25A degradation by the proteasome during the G1/S and G2/M phases promoting cell-cycle progression. Also regulates cell proliferation and apoptosis through deubiquitination of SUDS3 a regulator of histone deacetylation. Through activation of the Rho family GTPases RAC1A, CDC42 and RHOA, regulates cell migration. Through the cleavage of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains of the cytoplasmic innate immune receptors DDX58 and IFIH1 stimulates the cellular response to viral infection.

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Products

Antibodies (14)

Proteins (2)

Type

Over-Expression Lysate (1)

Primary (14)

Recombinant (1)

Target

USP17L2 / DUB3 (16)

Reactivity

Human (14)

Application

WB (14)

ELISA (6)

Host

rabbit (8)

mouse (6)

Isotype

IgG1,k (6)

Clonality

monoclonal mc (6)

polyclonal pc (8)

Format

APC Conjugated (1)

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (1)

Unconjugated (3)

Epitope

aa371-420 (4)

C-Terminus (3)

aa431-531 (1)

aa481-530 (1)

Publications

No (16)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (1)

Species

Human (2)

Source

293T Cells (1)

Wheat Germ Extract (1)

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USP17L2 / DUB3 Antibody (aa371-420) LS-C116937

Antibody:

USP17L2 / DUB3 Rabbit anti-Human Polyclonal (aa371-420) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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USP17L2 / DUB3 Antibody (aa371-420, HRP) LS-C466071

Antibody:

USP17L2 / DUB3 Rabbit anti-Human Polyclonal (aa371-420) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

USP17L2 / DUB3 Antibody (aa371-420, Biotin) LS-C466069

Antibody:

USP17L2 / DUB3 Rabbit anti-Human Polyclonal (aa371-420) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

USP17L2 / DUB3 Antibody (aa371-420, FITC) LS-C466070

Antibody:

USP17L2 / DUB3 Rabbit anti-Human Polyclonal (aa371-420) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

USP17L2 / DUB3 Antibody (aa481-530) LS-C205429

Antibody:

USP17L2 / DUB3 Rabbit anti-Human Polyclonal (aa481-530) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

USP17L2 / DUB3 Antibody (C-Terminus, HRP) LS-C473188

Antibody:

USP17L2 / DUB3 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

USP17L2 / DUB3 Antibody (C-Terminus, Biotin) LS-C473186

Antibody:

USP17L2 / DUB3 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

USP17L2 / DUB3 Antibody (C-Terminus, FITC) LS-C473187

Antibody:

USP17L2 / DUB3 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

USP17L2 / DUB3 Antibody (aa431-531) LS-C307310

Antibody:

USP17L2 / DUB3 Mouse anti-Human Monoclonal (aa431-531) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$705

Select

USP17L2 / DUB3 Antibody (HRP) LS-C541876

Antibody:

USP17L2 / DUB3 Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

100 µl/$904

Select

USP17L2 / DUB3 Antibody (Biotin) LS-C521745

Antibody:

USP17L2 / DUB3 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

100 µl/$904

Select

USP17L2 / DUB3 Antibody (FITC) LS-C531789

Antibody:

USP17L2 / DUB3 Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

100 µl/$904

Select

USP17L2 / DUB3 Antibody (APC) LS-C513530

Antibody:

USP17L2 / DUB3 Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

100 µl/$904

Select

USP17L2 / DUB3 Antibody (PE) LS-C649989

Antibody:

USP17L2 / DUB3 Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

100 µl/$904

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • PE

Select

Human USP17L2 / DUB3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92915

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

59.6 kDa

Price:

20 µg/$150

Select

Human USP17L2 / DUB3 Protein (Recombinant GST, N-terminus) (aa431-530) - LS-G64613

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

Viewing 1-16 of 16 product results

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