Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
UNC5C Antibody, Unc-5 homolog 3 Antibody, UNC5H3 Antibody, Netrin receptor UNC5C Antibody, Protein unc-5 homolog 3 Antibody, Protein unc-5 homolog C Antibody, Unc-5 homolog C (C. elegans) Antibody, Unc5 (C.elegans homolog) c Antibody
Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. Also involved in corticospinal tract axon guidances independently of DCC. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.
Formalin-fixed and paraffin-embedded human brain tissue with UNC5C Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Western blot of UNC5C Antibody in K562 cell line lysates (35 ug/lane). UNC5C (arrow) was detected using the purified antibody.
Flow cytometric of K562 cells using UNC5C Antibody (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.