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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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UNC5H3 / UNC5C Antibody (aa121‑170) LS‑C187315
UNC5C antibody LS-C187315 is an unconjugated rabbit polyclonal antibody to UNC5C (UNC5H3) from human, mouse, rat and other species. Validated for WB.
Catalog
Size
Price
LS-C187315-50
50 µg (1 mg/ml)
Unavailable

Popular UNC5H3 / UNC5C Products

Jurkat cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 6-18%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Horse, Rabbit, Zebrafish
Applications: Western blot
Anti-UNC5H3 / UNC5C antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8305 dilution 3.75 ug/ml.
Species: Human, Monkey, Mouse, Rat, Bat, Hamster
Applications: IHC, IHC - Paraffin, Peptide Enzyme-Linked Immunosorbent Assay
Formalin-fixed and paraffin-embedded human brain tissue with UNC5C Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Flow Cytometry
Antibody
Species: Human
Applications: IHC, Western blot, ELISA
Western blot analysis of extracts of K562 cells.
Species: Human
Applications: IHC, Western blot, Flow Cytometry

Product Description

UNC5C antibody LS-C187315 is an unconjugated rabbit polyclonal antibody to UNC5C (UNC5H3) from human, mouse, rat and other species. Validated for WB.
About UNC5H3 / UNC5C
Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. Also involved in corticospinal tract axon guidances independently of DCC. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. O95185 NM_003728 NP_003719.3

UNC5C Antibody, Unc-5 homolog 3 Antibody, UNC5H3 Antibody, Netrin receptor UNC5C Antibody, Protein unc-5 homolog 3 Antibody, Protein unc-5 homolog C Antibody, Unc-5 homolog C (C. elegans) Antibody, Unc5 (C.elegans homolog) c Antibody


Specifications

Target
Human UNC5H3 / UNC5C
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Chicken, Zebrafish (tested or 100% immunogen sequence identity)
Predicted
Hamster, Xenopus (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with FITC, Biotin, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
  • (applications tested for the base form of this product only)
Immunogen
UNC5H3 / UNC5C antibody was raised against synthetic peptide located between aa121-170 of human UNC5C (O95185-2). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Mouse, Rat, Elephant, Panda, Dog, Bovine, Bat, Rabbit, Horse, Pig, Opossum, Guinea pig, Turkey, Zebra finch, Chicken, Platypus, Lizard (100%); Orangutan, Hamster, Xenopus, Medaka, Pufferfish (92%).
Blocking Peptide
LS-E23424 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C187315. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa121-170
Specificity
Human UNC5H3 / UNC5C
Presentation
Lyophilized from PBS
Reconstitution
50 µl Distilled water
Storage
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western blot of Human 293T . UNC5C antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human 293T . UNC5C antibody dilution 1.0 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot of Human 293T . UNC5C antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human 293T . UNC5C antibody dilution 1.0 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot of Human 293T . UNC5C antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human 293T . UNC5C antibody dilution 1.0 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot of Human 293T . UNC5C antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human 293T . UNC5C antibody dilution 1.0 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/21/2018

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