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UMPS / OPRT

uridine monophosphate synthetase

UMPS / OPRT encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.

Gene Name: uridine monophosphate synthetase
Synonyms: UMPS, OMPdecase, OPRT, OPRTase, UMP synthase
Target Sequences: NM_000373 NP_000364.1 P11172

☰ Filters
Antibodies (39)
Proteins (8)
Over-Expression Lysate (2)
Primary (39)
Recombinant (6)
UMPS / OPRT (47)
Human (31)
Mouse (20)
Rat (13)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Hamster (3)
Orangutan (3)
Rabbit (3)
IHC (7)
IHC-P (2)
WB (32)
ELISA (5)
ICC (1)
IF (6)
IP (3)
Peptide-ELISA (1)
rabbit (38)
mouse (1)
IgG (19)
IgG2b,k (1)
monoclonal mc (1)
polyclonal pc (38)
2B10 (1)
APC (2)
APC Conjugated (2)
Biotin Conjugated (4)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (19)
aa205-480 (8)
aa311-481 (8)
aa398-447 (4)
Tyr37 (1)
aa350-400 (1)
aa430-480 (1)
No (47)
GST (1)
GST, N-terminus (1)
His (1)
His-T7 (2)
Myc-DDK (Flag) (3)
Human (6)
Mouse (1)
293T Cells (1)
E. coli (3)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (2)
UMPS / OPRT Antibody
Select
UMPS / OPRT Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321
UMPS / OPRT Antibody - Western blot of lysate from HeLa cell line with Phospho-HUMAN-UMPS (Y37). control. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 35 ug.
Select
UMPS / OPRT Rabbit anti-Human Polyclonal (Tyr37) Antibody
Human
WB
Unconjugated
400 µl/$393
Select
UMPS / OPRT Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$341
UMPS / OPRT Antibody - Immunohistochemistry of paraffin-embedded rat liver tissue.
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UMPS / OPRT Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
UMPS / OPRT Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
UMPS / OPRT Antibody - IHC image of UMPS Antibody diluted at 1:100 and staining in paraffin-embedded human cervical cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Select
UMPS / OPRT Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF
Unconjugated
50 µg/$294; 100 µg/$360
UMPS / OPRT Antibody - Immunohistochemistry of paraffin-embedded Human brain tissue  using UMPS Polyclonal Antibody at dilution of 1:40(×200)
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UMPS / OPRT Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
UMPS / OPRT Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
UMPS / OPRT Antibody - Immunochemical staining of human UMPS in human large intestine with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
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UMPS / OPRT Rabbit anti-Human Polyclonal Antibody
Human
IHC-P, IP, WB
Unconjugated
100 µl/$412
UMPS / OPRT Antibody - Immunohistochemistry of paraffin-embedded Human brain tissue  using UMPS Polyclonal Antibody at dilution of 1:40(×200)
Select
UMPS / OPRT Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
UMPS / OPRT Antibody - UMPS monoclonal antibody (M06), clone 2B10. Western blot of UMPS expression in IMR-32.
Select
UMPS / OPRT Mouse anti-Human Monoclonal (2B10) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
UMPS / OPRT Antibody - Detection of Human and Mouse UMPS by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa, 293T, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells. Antibodies: Affinity purified rabbit anti-UMPS antibody used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
Select
UMPS / OPRT Rabbit anti-Human Polyclonal (aa430-480) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
UMPS / OPRT Antibody - Western blot analysis of extracts of Jurkat cells using UMPS antibody. The lane on the left was treated with blocking peptide.
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UMPS / OPRT Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
UMPS / OPRT Antibody - Immunofluorescence analysis of NIH/3T3 cells using UMPS Polyclonal Antibody at dilution of 1:100 (40x lens).Blue: DAPI for nuclear staining.
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UMPS / OPRT Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
UMPS / OPRT Antibody - Western blot of UMPS / OPRT antibody.
Select
UMPS / OPRT Rabbit anti-Mouse Polyclonal (aa311-481) Antibody
Mouse, Rat
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
UMPS / OPRT Antibody - Western blot of UMPS / OPRT antibody.
Select
UMPS / OPRT Rabbit anti-Mouse Polyclonal (aa311-481) (HRP) Antibody
Mouse, Rat
WB
HRP Conjugated
100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639
UMPS / OPRT Antibody - Western blot of UMPS / OPRT antibody.
Select
UMPS / OPRT Rabbit anti-Mouse Polyclonal (aa311-481) (Biotin) Antibody
Mouse, Rat
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
UMPS / OPRT Antibody - Western blot of UMPS / OPRT antibody.
Select
UMPS / OPRT Rabbit anti-Mouse Polyclonal (aa311-481) (FITC) Antibody
Mouse, Rat
WB
FITC Conjugated
100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765
UMPS / OPRT Antibody - Western blot of UMPS / OPRT antibody.
Select
UMPS / OPRT Rabbit anti-Mouse Polyclonal (aa311-481) (APC, Cy7) Antibody
Mouse, Rat
WB
APC, Cy7 Conjugated
100 µl/$513; 200 µl/$666; 500 µl/$1,175; 1 ml/$1,441; 2 ml/$2,017; 5 ml/$3,781
UMPS / OPRT Antibody - Western blot of UMPS / OPRT antibody.
Select
UMPS / OPRT Rabbit anti-Mouse Polyclonal (aa311-481) (Cy3) Antibody
Mouse, Rat
WB
Cy3 Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
UMPS / OPRT Antibody - Western blot of UMPS / OPRT antibody.
Select
UMPS / OPRT Rabbit anti-Mouse Polyclonal (aa311-481) (PE) Antibody
Mouse, Rat
WB
PE Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
UMPS / OPRT Antibody - 721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
UMPS / OPRT Rabbit anti-Human Polyclonal (aa398-447) Antibody
Human
WB
Unconjugated
100 µl/$424
UMPS / OPRT Antibody - Western blot analysis of extracts of various cell lines, using UMPS antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 30s.
Select
UMPS / OPRT Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
UMPS / OPRT Antibody - Western blot of UMPS / OPRT antibody.
Select
UMPS / OPRT Rabbit anti-Human Polyclonal (aa205-480) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
Select
UMPS / OPRT Rabbit anti-Human Polyclonal (aa350-400) Antibody
Human
IP
Unconjugated
10 µg/$295; 100 µl/$514
Viewing 1-25 of 47 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).