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Anti-UIMC1 / RAP80 Antibody (N-Terminus) IHC-plus™ LS-B2707

Note: This antibody replaces LS-C34742
Catalog Size Price
LS-B2707-50 50 µg (1 mg/ml) Unavailable

Related Products

22 UIMC1 / RAP80 Antibodies

Most Popular UIMC1 / RAP80 Antibodies

Anti-UIMC1 / RAP80 Antibody (C-Terminus) IHC-plus™ LS-B2706
Rabbit Polyclonal (IgG) to Human UIMC1 / RAP80
Human, Mouse
IHC, IHC - Paraffin, Western blot, ELISA
Unconjugated
Anti-UIMC1 / RAP80 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2706 concentration 5 ug/ml.
Anti-UIMC1 / RAP80 Antibody (N-Terminus) IHC-plus™ LS-B2707
Rabbit Polyclonal (IgG) to Human UIMC1 / RAP80
Human, Mouse
IHC, IHC - Paraffin, Western blot, ELISA
Unconjugated
Anti-UIMC1 / RAP80 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2707 concentration 5 ug/ml.
Anti-UIMC1 / RAP80 Antibody (aa535-548) IHC-plus™ LS-B7372
Goat Polyclonal to Human UIMC1 / RAP80
Human, Monkey
IHC, IHC - Paraffin, ELISA
Unconjugated
Anti-UIMC1 / RAP80 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7372 concentration 3.75 ug/ml.
Anti-UIMC1 / RAP80 Antibody LS-C346307
Rabbit Polyclonal (IgG) to Human UIMC1 / RAP80
Human, Mouse, Rat
IHC, Immunofluorescence, Western blot
Unconjugated
Immunofluorescence analysis of U20S cells.
Anti-UIMC1 / RAP80 Antibody (aa600-650) IHC-plus™ LS-B15284
Rabbit Polyclonal (IgG) to Human UIMC1 / RAP80
Human
IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Unconjugated
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

100% Guaranteed
Rabbit Polyclonal (IgG) to Human UIMC1 / RAP80
Human, Mouse
IHC, IHC - Paraffin, Western blot, ELISA
Unconjugated

Details

Human UIMC1 / RAP80
Rabbit
Human, Mouse (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC
  • IHC - Paraffin (5 µg/ml)
  • Western blot (1 - 2 µg/ml)
  • ELISA

Specificity and Use

LS-E30388 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-B2707. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
N-Terminus
Immunohistochemistry: LS-B2707 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2707 was determined to be 5 ug/ml.

Packaging

PBS, 0.02% sodium azide.
Store at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze thaw cycles.
For research use only.

About UIMC1 / RAP80

Q96RL1 NM_016290 NP_057374.3

UIMC1 Antibody, BRCA1-A complex subunit RAP80 Antibody, Receptor associated protein 80 Antibody, RAP80 Antibody, RXRIP110 Antibody, X2HRIP110 Antibody, Receptor-associated protein 80 Antibody

Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Plays a central role in the BRCA1-A complex by specifically binding 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.

Immunohistochemistry

Anti-UIMC1 / RAP80 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2707 concentration 5 ug/ml.
Anti-UIMC1 / RAP80 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2707 concentration 5 ug/ml.

Immunofluorescence

Immunofluorescence of RAP80 in human spleen tissue with RAP80 antibody at 20 µg/mL.
Immunofluorescence of RAP80 in human spleen tissue with RAP80 antibody at 20 µg/mL.

Immunofluorescence

Immunofluorescence of RAP80 in human spleen tissue with RAP80 antibody at 20 ug/ml.
Immunofluorescence of RAP80 in human spleen tissue with RAP80 antibody at 20 ug/ml.

Western blot

Western blot analysis of RAP80 in 293 cell lysate in (A) the absence and (B) presence of blocking peptide with RAP80 antibody at 1 µg/mL.
Western blot analysis of RAP80 in 293 cell lysate in (A) the absence and (B) presence of blocking peptide with RAP80 antibody at 1 µg/mL.

Western blot

Immunohistochemistry of RAP80 in human spleen tissue with RAP80 antibody at 2.5 µg/ml.
Immunohistochemistry of RAP80 in human spleen tissue with RAP80 antibody at 2.5 µg/ml.

Requested From: 
Date Requested: 4/26/2018

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