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Anti-UIMC1 / RAP80 Antibody (C-Terminus) LS-C93646

Catalog Size Price
LS-C93646-100 100 µg (1 mg/ml) Unavailable

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17 UIMC1 / RAP80 Antibodies

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Anti-UIMC1 / RAP80 Antibody (N-Terminus) IHC-plus™ LS-B2707
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Anti-UIMC1 / RAP80 Antibody (C-Terminus) LS-C287625
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Anti-UIMC1 / RAP80 Antibody LS-C346307
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100% Guaranteed
Rabbit Polyclonal to Human UIMC1 / RAP80
Human
Western blot, Immunoprecipitation, ELISA
Unconjugated

Details

Human UIMC1 / RAP80
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • Western blot (1:1000 - 1:2000)
  • Immunoprecipitation
  • ELISA

Specificity and Use

UIMC1 / RAP80 antibody was raised against the epitope recognized maps to a region between residue 650 and the C-terminus (residue 719) of human Receptor Associated Protein 80 using the numbering given in entry NP_057374.3 (GeneID 51720).
C-Terminus
Species cross-reactivity: Human. Other species have not been tested.
Suitable for use in ELISA, Western Blot and Immunoprecipitation. Western Blot: 1:1000-1:2000.

Packaging

Tris-citrate/phosphate buffer, pH 7 to 8
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
For research use only.

About UIMC1 / RAP80

Q96RL1 NM_016290 NP_057374.3

UIMC1 Antibody, BRCA1-A complex subunit RAP80 Antibody, Receptor associated protein 80 Antibody, RAP80 Antibody, RXRIP110 Antibody, X2HRIP110 Antibody, Receptor-associated protein 80 Antibody

Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Plays a central role in the BRCA1-A complex by specifically binding 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.

Requested From: 
Date Requested: 6/28/2017

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