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UCP3

uncoupling protein 3 (mitochondrial, proton carrier)

Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. The different UCPs have tissue-specific expression; this gene is primarily expressed in skeletal muscle. This gene's protein product is postulated to protect mitochondria against lipid-induced oxidative stress. Expression levels of this gene increase when fatty acid supplies to mitochondria exceed their oxidation capacity and the protein enables the export of fatty acids from mitochondria. UCPs contain the three solcar protein domains typically found in MACPs. Two splice variants have been found for this gene.

Gene Name: uncoupling protein 3 (mitochondrial, proton carrier)
Family/Subfamily: Transporter , Mitochondrial carrier
Synonyms: UCP3, SLC25A9, UCP 3, Uncoupling protein-3
Target Sequences: NM_003356 NP_003347.1 P55916

☰ Filters
Antibodies (19)
ELISA Kits (9)
Proteins (5)
Custom (5)
Over-Expression Lysate (4)
Primary (19)
Recombinant (1)
Sandwich (4)
UCP3 (33)
Human (20)
Mouse (11)
Rat (10)
Dog (2)
Pig (2)
IHC (7)
IHC-P (1)
WB (13)
ELISA (10)
IF (3)
Peptide-ELISA (2)
rabbit (18)
mouse (1)
IgG (14)
IgG2a (1)
monoclonal mc (1)
polyclonal pc (18)
6B8C6 (1)
12 x 8-Well Microstrips (1)
96-Well Strip Plate (8)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (16)
C-Terminus (2)
Arg308 (1)
C-terminal (1)
aa110-124 (1)
aa125-175 (1)
aa259-308 (1)
No (33)
Plasma (4)
Serum (4)
Tissue Homogenates (2)
GST (1)
Myc-DDK (Flag) (4)
Human (3)
293T Cells (2)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
UCP3 Antibody - Western blot analysis of UCP3 expression in L929 (A); rat kidney (B) whole cell lysates.
Select
UCP3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Dog, Rat, Pig, Human
WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
UCP3 Antibody - Immunohistochemistry of paraffin-embedded human liver cancer using UCP3 antibody at dilution of 1:200 (x400 lens).
Select
UCP3 Rabbit anti-Human Polyclonal Antibody
Mouse
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
UCP3 ELISA Kit
Select
Sandwich
12 x 8-Well Microstrips
Human
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Select
UCP3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$867
UCP3 Antibody - Western blot of UCP3 in human heart lysate in the 1) absence and 2) presence of immunizing peptide, 3) mouse heart and 4) rat heart using Polyclonal Antibody to UCP3 at 1.0 ug/ml.
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UCP3 Rabbit anti-Human Polyclonal (aa125-175) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µg/$386
UCP3 Antibody - Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using antibody at dilution of 1:100.
Select
UCP3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
UCP3 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
UCP3 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
UCP3 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
Select
UCP3 Mouse anti-Human Monoclonal (6B8C6) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µl/$459
Select
UCP3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$832
Select
UCP3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
UCP3 Antibody - 1:200 staining human heart tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
UCP3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
UCP3 Antibody - Western blot of extracts of skeletal muscle cell and SGC-7901 cell line, using UCP3 antibody.
Select
UCP3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
UCP3 Antibody - Western blot of UCP3 antibody
Select
UCP3 Rabbit anti-Human Polyclonal (C-terminal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
UCP3 Antibody - Immunofluorescence analysis of C6 cells using UCP3 Polyclonal Antibody at dilution of 1:100.Blue: DAPI for nuclear staining.
Select
UCP3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
UCP3 Antibody - Western blot analysis of lysate from Jurkat cells, using UCP3 antibody.
Select
UCP3 Rabbit anti-Human Polyclonal (aa259-308) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Select
UCP3 Rabbit anti-Human Polyclonal (aa110-124) Antibody
Human
ELISA
Unconjugated
200 µg/$1,027
UCP3 Antibody - Western blot of UCP3 (R308) pAb in extracts from Jurkat cells.
Select
UCP3 Rabbit anti-Human Polyclonal (Arg308) Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
Select
UCP3 Rabbit anti-Human Polyclonal Antibody
Human
Unconjugated
100 µg/$341
UCP3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
34 kDa
20 µg/$150
UCP3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
29.6 kDa
20 µg/$150
UCP3 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
UCP3 ELISA Kit
Select
Custom
96-Well Strip Plate
Dog
Colorimetric - 450nm (TMB)
1 Plate/$929
UCP3 ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$783
Viewing 1-25 of 33 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).