Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
Specificity and Use
UCHL1 / PGP9.5 antibody was raised against a synthetic peptide made to an internal portion of the human UCHL1 protein sequence (between residues 100-200). UniProt P09936. Percent identity by BLAST analysis: Rat (99%); Bovine (92%).
Rabbit Polyclonal to PGP9.5 - Peripheral Nerve Fiber marker.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.
Anti-UCHL1 / PGP9.5 antibody IHC of human brain, substantia nigra. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B489 concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of UCHL1 in mouse brain lysate. ECL detection, 60 seconds. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of UCHL1 in mouse brain lysate using LS-C2926. ECL detection, 60 seconds. This image was taken for the unconjugated form of this product. Other forms have not been tested.