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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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UBR1 Antibody (aa245‑274) LS‑C157012
UBR1 antibody LS-C157012 is an unconjugated rabbit polyclonal antibody to UBR1 from human and mouse. Validated for WB.
Catalog
Size
Price
LS-C157012-400
400 µl
Unavailable

Popular UBR1 Products

Antibody
Species: Mouse
Applications: Western blot, ELISA
Antibody
Species: Mouse
Applications: Western blot, ELISA
Antibody
Species: Human, Mouse
Applications: Western blot, ELISA
Immunohistochemical analysis of UBR1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Species: Human, Monkey, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot
Western blot of Ubr1 antibody
Species: Human, Mouse
Applications: IHC, Western blot, ELISA

Product Description

UBR1 antibody LS-C157012 is an unconjugated rabbit polyclonal antibody to UBR1 from human and mouse. Validated for WB.
About UBR1
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. May be involved in pancreatic homeostasis. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth. Q8IWV7 AI192195 NP_777576.1

UBR1 Antibody, E3a ligase Antibody, JBS Antibody, N-recognin-1 Antibody, Ubiquitin ligase E3 alpha-I Antibody


Specifications

Target
Human UBR1
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (1:1000)
Epitope
aa245-274
Specificity
This UBR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 245-274 amino acids from the N-terminal region of human UBR1.
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (0)


Customer Reviews (0)


Images


Western blot

UBR1 Antibody western blot of mouse liver tissue lysates (35 ug/lane). The UBR1 antibody detected the UBR1 protein (arrow).
UBR1 Antibody western blot of mouse liver tissue lysates (35 ug/lane). The UBR1 antibody detected the UBR1 protein (arrow).

Western blot

UBR1 Antibody western blot of mouse liver tissue lysates (35 ug/lane). The UBR1 antibody detected the UBR1 protein (arrow).
UBR1 Antibody western blot of mouse liver tissue lysates (35 ug/lane). The UBR1 antibody detected the UBR1 protein (arrow).

Western blot

UBR1 Antibody western blot of mouse liver tissue lysates (35 ug/lane). The UBR1 antibody detected the UBR1 protein (arrow).
UBR1 Antibody western blot of mouse liver tissue lysates (35 ug/lane). The UBR1 antibody detected the UBR1 protein (arrow).

Western blot

UBR1 Antibody western blot of mouse liver tissue lysates (35 ug/lane). The UBR1 antibody detected the UBR1 protein (arrow).
UBR1 Antibody western blot of mouse liver tissue lysates (35 ug/lane). The UBR1 antibody detected the UBR1 protein (arrow).


Requested From: 
Date Requested: 6/19/2018

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