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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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UBN1 / Ubinuclein 1 Antibody (aa974‑1023) LS‑C81099
Ubinuclein 1 antibody LS-C81099 is an unconjugated rabbit polyclonal antibody to Ubinuclein 1 (UBN1) from human, bovine, dog and other species. Validated for WB.
Catalog
Size
Price
LS-C81099-50
50 µg (1 mg/ml)
Unavailable

Popular UBN1 / Ubinuclein 1 Products

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Species: Human
Applications: IHC, Western blot, ELISA

Product Description

Ubinuclein 1 antibody LS-C81099 is an unconjugated rabbit polyclonal antibody to Ubinuclein 1 (UBN1) from human, bovine, dog and other species. Validated for WB.
About UBN1 / Ubinuclein 1
Acts as a novel regulator of senescence. Involved in the formation of senescence-associated heterochromatin foci (SAHF), which represses expression of proliferation-promoting genes. Binds to proliferation-promoting genes. May be required for replication-independent chromatin assembly. Q9NPG3 NM_016936 NP_058632.2

UBN1 Antibody, HIRA-binding protein Antibody, Protein VT4 Antibody, VT Antibody, Ubinuclein-1 Antibody, VT4 Antibody, Ubinuclein 1 Antibody


Specifications

Target
Human UBN1 / Ubinuclein 1
Host
Rabbit
Reactivity
Human, Bovine, Dog, Guinea pig, Rabbit (tested or 100% immunogen sequence identity)
Predicted
Monkey, Mouse, Rat, Bat, Hamster, Horse (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
  • (applications tested for the base form of this product only)
Immunogen
Synthetic peptide located between aa974-1023 of human UBN1 (Q9NPG3, NP_058632). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Elephant, Panda, Dog, Bovine, Opossum, Guinea pig (100%); Marmoset, Mouse, Rat, Hamster, Bat, Horse, Turkey, Zebra finch (92%); Rabbit (85%).
Epitope
aa974-1023
Specificity
Human UBN1
Usage
ELISA titer using peptide based assay: 1:62500. Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1:50000 - 100000 as second antibody.
Presentation
Lyophilized from PBS with 2% sucrose
Reconstitution
50 µl Distilled Water.
Storage
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 6-18%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 6-18%. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 6-18%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 6-18%. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 6-18%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 6-18%. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 6-18%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 6-18%. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/21/2018

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