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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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UBE2L6 Antibody (aa123‑153) LS‑C99504
UBE2L6 antibody LS-C99504 is an unconjugated rabbit polyclonal antibody to human UBE2L6. Validated for IHC and WB. Cited in 1 publication.
Catalog
Size
Price
LS-C99504-400
400 µl
Unavailable

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Product Description

UBE2L6 antibody LS-C99504 is an unconjugated rabbit polyclonal antibody to human UBE2L6. Validated for IHC and WB. Cited in 1 publication.
About UBE2L6
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. O14933 NM_004223 NP_004214.1

UBE2L6 Antibody, Ubiquitin carrier protein L6 Antibody, Ubiquitin-protein ligase L6 Antibody, UBCH8 Antibody, RIG-B Antibody


Specifications

Target
Human UBE2L6
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Ammonium sulfate precipitation
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:10 - 1:50)
  • Western blot (1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Blocking Peptide
LS-E6864 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C99504. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa123-153
Specificity
This UBE2L6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-153 amino acids from the C-terminal region of human UBE2L6.
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (1)

1
Mechanism for ubiquitylation of the leukemia fusion proteins AML1-ETO and PML-RARalpha. Krmer OH, Mller S, Buchwald M, Reichardt S, Heinzel T. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2008 22:1369-79. [PubMed:18073335]

Customer Reviews (0)


Images


Immunohistochemistry

Formalin-fixed and paraffin-embedded breast carcinoma tissue reacted with UBE2L6 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Formalin-fixed and paraffin-embedded breast carcinoma tissue reacted with UBE2L6 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Western blot

The UBE2L6 Antibody is used in Western blot to detect UBE2L6 in HL-60 cell lysate.
The UBE2L6 Antibody is used in Western blot to detect UBE2L6 in HL-60 cell lysate.

Immunohistochemistry

Formalin-fixed and paraffin-embedded breast carcinoma tissue reacted with UBE2L6 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Formalin-fixed and paraffin-embedded breast carcinoma tissue reacted with UBE2L6 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Western blot

The UBE2L6 Antibody is used in Western blot to detect UBE2L6 in HL-60 cell lysate.
The UBE2L6 Antibody is used in Western blot to detect UBE2L6 in HL-60 cell lysate.

Immunohistochemistry

Formalin-fixed and paraffin-embedded breast carcinoma tissue reacted with UBE2L6 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Formalin-fixed and paraffin-embedded breast carcinoma tissue reacted with UBE2L6 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Western blot

The UBE2L6 Antibody is used in Western blot to detect UBE2L6 in HL-60 cell lysate.
The UBE2L6 Antibody is used in Western blot to detect UBE2L6 in HL-60 cell lysate.

Immunohistochemistry

Formalin-fixed and paraffin-embedded breast carcinoma tissue reacted with UBE2L6 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Formalin-fixed and paraffin-embedded breast carcinoma tissue reacted with UBE2L6 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Western blot

The UBE2L6 Antibody is used in Western blot to detect UBE2L6 in HL-60 cell lysate.
The UBE2L6 Antibody is used in Western blot to detect UBE2L6 in HL-60 cell lysate.


Requested From: 
Date Requested: 6/22/2018

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