UBC / Ubiquitin C

ubiquitin C

Ubiquitin: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.

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Products

Antibodies (10)

ELISA Kits (6)

Type

Primary (10)

Sandwich (6)

Target

UBC / Ubiquitin C (16)

Reactivity

Human (11)

Mouse (5)

Rat (6)

Bovine (2)

Chicken (1)

Monkey (1)

Porcine (1)

Rabbit (1)

Sheep (1)

Application

IHC (8)

IHC-P (3)

WB (8)

ELISA (2)

IF (4)

Host

rabbit (8)

mouse (2)

Product Group

IHCPlus (2)

Isotype

IgG (4)

IgG2a (2)

Clonality

monoclonal mc (2)

polyclonal pc (8)

Clone

5B9.B3 (1)

Format

96-Well Strip Plate (6)

Unconjugated (10)

Epitope

aa1-32 (1)

aa36-66 (1)

Publications

No (15)

Yes (1)

Sample Type

Plasma (1)

Serum (1)

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IHC-plus™ UBC / Ubiquitin C Antibody (aa1-32) LS-B3386

(5.0) Rating

(1) Publication(s)

Antibody:

UBC / Ubiquitin C Rabbit anti-Human Polyclonal (aa1-32) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

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IHC-plus™ UBC / Ubiquitin C Antibody (aa36-66) LS-B3621

(4.0) Rating

Antibody:

UBC / Ubiquitin C Rabbit anti-Human Polyclonal (aa36-66) Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

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UBC / Ubiquitin C Antibody LS-C2924

Antibody:

UBC / Ubiquitin C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

0.05 ml/$386

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UBC / Ubiquitin C Antibody LS-C771557

Antibody:

UBC / Ubiquitin C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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UBC / Ubiquitin C Antibody LS-C755367

Antibody:

UBC / Ubiquitin C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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UBC / Ubiquitin C Antibody (clone 5B9.B3) LS-C760046

Antibody:

UBC / Ubiquitin C Mouse anti-Bovine Monoclonal (5B9.B3) Antibody

Reactivity:

Mouse, Bovine, Rat, Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$461

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UBC / Ubiquitin C Antibody LS-C667678

Antibody:

UBC / Ubiquitin C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321

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UBC / Ubiquitin C Antibody LS-C760045

Antibody:

UBC / Ubiquitin C Mouse anti-Bovine Monoclonal Antibody

Reactivity:

Mouse, Bovine, Rat, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

100 µg/$453

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UBC / Ubiquitin C Antibody LS-C831568

Antibody:

UBC / Ubiquitin C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC

Format:

Unconjugated

Price:

20 µl/$250; 60 µl/$286; 120 µl/$349; 200 µl/$439

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UBC / Ubiquitin C Antibody LS-C831604

Antibody:

UBC / Ubiquitin C Rabbit anti-Rat Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

IHC

Format:

Unconjugated

Price:

20 µl/$250; 60 µl/$286; 120 µl/$349; 200 µl/$439

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Human UBC / Ubiquitin C (Sandwich ELISA) ELISA Kit - LS-F37902

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Chicken UBC / Ubiquitin C (Sandwich ELISA) ELISA Kit - LS-F48987

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Monkey UBC / Ubiquitin C (Sandwich ELISA) ELISA Kit - LS-F48988

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Rabbit UBC / Ubiquitin C (Sandwich ELISA) ELISA Kit - LS-F48990

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Porcine UBC / Ubiquitin C (Sandwich ELISA) ELISA Kit - LS-F48989

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Sheep UBC / Ubiquitin C (Sandwich ELISA) ELISA Kit - LS-F48991

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Sheep

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$760

Viewing 1-16 of 16 product results

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