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UBA3 / UBE1C

ubiquitin-like modifier activating enzyme 3

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene Name: ubiquitin-like modifier activating enzyme 3
Synonyms: UBA3, HUBA3, UBE1C, Ubiquitin-activating enzyme 3, NEDD8-activating enzyme E1C, Nedd8-activating enzyme hUba3
Target Sequences: NM_003968 NP_003959.3 Q8TBC4

☰ Filters
Antibodies (26)
Proteins (8)
ELISA Kits (4)
Custom (3)
Over-Expression Lysate (4)
Primary (26)
Recombinant (4)
Sandwich (1)
UBA3 / UBE1C (38)
Human (28)
Mouse (21)
Rat (14)
Bat (4)
Bovine (3)
Chicken (3)
Chimpanzee (3)
Dog (9)
Gibbon (3)
Hamster (4)
Horse (4)
Monkey (9)
Orangutan (3)
Pig (3)
Rabbit (3)
Sheep (1)
Zebrafish (3)
IHC (13)
IHC-P (4)
WB (23)
ELISA (7)
IF (2)
Peptide-ELISA (1)
rabbit (19)
mouse (7)
IgG (13)
IgG1 (6)
IgG2b (1)
monoclonal mc (7)
polyclonal pc (19)
OTI1B10 (2)
OTI1B9 (2)
OTI3F9 (2)
OTI7H6 (1)
96-Well Strip Plate (4)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
Carrier-free (3)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (18)
aa1-463 (7)
aa415-445 (7)
aa35-84 (4)
aa409-448 (1)
No (38)
Plasma (1)
Serum (1)
Tissue Homogenates (1)
GST (1)
His (1)
Myc-DDK (Flag) (6)
Human (6)
293T Cells (2)
E. coli (1)
HEK 293 Cells (4)
Wheat Germ Extract (1)
Purified (2)
UBA3 / UBE1C Antibody - Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-UBA3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)
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UBA3 / UBE1C Mouse anti-Human Monoclonal (aa1-463) (OTI7H6) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
UBA3 / UBE1C Antibody
Select
UBA3 / UBE1C Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$575
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UBA3 / UBE1C Rabbit anti-Human Polyclonal (aa415-445) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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UBA3 / UBE1C Rabbit anti-Human Polyclonal (aa415-445) (Biotin) Antibody
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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UBA3 / UBE1C Rabbit anti-Human Polyclonal (aa415-445) (FITC) Antibody
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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UBA3 / UBE1C Rabbit anti-Human Polyclonal (aa415-445) (APC) Antibody
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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UBA3 / UBE1C Rabbit anti-Human Polyclonal (aa415-445) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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UBA3 / UBE1C Rabbit anti-Human Polyclonal (aa415-445) (PE) Antibody
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
UBA3 / UBE1C Antibody - Immunohistochemistry of paraffin-embedded human testis tissue at dilution 1:100
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UBA3 / UBE1C Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
UBA3 / UBE1C Antibody - 1:100 staining rat brain tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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UBA3 / UBE1C Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
UBA3 / UBE1C Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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UBA3 / UBE1C Rabbit anti-Human Polyclonal (aa415-445) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
UBA3 / UBE1C Antibody - UBE1C antibody IHC-paraffin. IHC(P): Mouse Testis Tissue.
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UBA3 / UBE1C Rabbit anti-Human Polyclonal (aa409-448) Antibody
Rat, Hamster, Horse, Bat, Mouse, Sheep, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
UBA3 / UBE1C Antibody - Immunohistochemistry of paraffin-embedded mouse kidney tissue.
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UBA3 / UBE1C Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
UBA3 / UBE1C Rabbit anti-Human Polyclonal Antibody
Human
IF
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
UBA3 / UBE1C Antibody - Immunofluorescence analysis of U2OS cells using UBA3 Polyclonal Antibody at dilution of 1:100.Blue: DAPI for nuclear staining.
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UBA3 / UBE1C Rabbit anti-Human Polyclonal Antibody
Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
UBA3 / UBE1C Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY UBA3. (Right lane) cDNA for 48 hrs and lysed
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UBA3 / UBE1C Mouse anti-Human Monoclonal (aa1-463) (OTI1B10) Antibody
Mouse, Dog, Rat, Human, Monkey
WB
Unconjugated
100 µl/$434
UBA3 / UBE1C Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY UBA3. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-UBA3. (1:500)
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UBA3 / UBE1C Mouse anti-Human Monoclonal (aa1-463) (Carrier-free) (OTI1B10) Antibody
Mouse, Dog, Rat, Human, Monkey
WB
Unconjugated, Carrier-free
100 µg/$511
UBA3 / UBE1C Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY UBA3. (Right lane) cDNA for 48 hrs and lysed
Select
UBA3 / UBE1C Mouse anti-Human Monoclonal (aa1-463) (OTI1B9) Antibody
Mouse, Dog, Rat, Human, Monkey
WB
Unconjugated
100 µl/$434
UBA3 / UBE1C Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY UBA3. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-UBA3. (1:500)
Select
UBA3 / UBE1C Mouse anti-Human Monoclonal (aa1-463) (Carrier-free) (OTI1B9) Antibody
Mouse, Dog, Rat, Human, Monkey
WB
Unconjugated, Carrier-free
100 µg/$511
UBA3 / UBE1C Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY UBA3. (Right lane) cDNA for 48 hrs and lysed
Select
UBA3 / UBE1C Mouse anti-Human Monoclonal (aa1-463) (OTI3F9) Antibody
Mouse, Dog, Rat, Human, Monkey
WB
Unconjugated
100 µl/$434
UBA3 / UBE1C Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY UBA3. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-UBA3. (1:500)
Select
UBA3 / UBE1C Mouse anti-Human Monoclonal (aa1-463) (Carrier-free) (OTI3F9) Antibody
Mouse, Dog, Rat, Human, Monkey
WB
Unconjugated, Carrier-free
100 µg/$511
UBA3 / UBE1C Antibody - UBA3 / UBE1C antibody Western blot of Fetal Pancreas lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UBA3 / UBE1C Rabbit anti-Human Polyclonal (aa35-84) Antibody
Human
WB
Unconjugated
100 µl/$424
UBA3 / UBE1C Antibody - UBA3 / UBE1C antibody Western blot of Fetal Pancreas lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UBA3 / UBE1C Rabbit anti-Human Polyclonal (aa35-84) (HRP) Antibody
Chicken, Zebrafish, Pig, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Human, Monkey, Gibbon, Orangutan, Chimpanzee
WB
HRP Conjugated
100 µl/$469
UBA3 / UBE1C Antibody - UBA3 / UBE1C antibody Western blot of Fetal Pancreas lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
UBA3 / UBE1C Rabbit anti-Human Polyclonal (aa35-84) (FITC) Antibody
Chicken, Zebrafish, Pig, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Human, Monkey, Gibbon, Orangutan, Chimpanzee
WB
FITC Conjugated
100 µl/$469
UBA3 / UBE1C Antibody - Sample (30 ug of whole cell lysate) A: A431 10% SDS PAGE UBA3 / UBE1C antibody diluted at 1:3000
Select
UBA3 / UBE1C Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$450
Viewing 1-25 of 38 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).