TYK2

tyrosine kinase 2

TYK2 is a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.

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Products

Antibodies (53)

ELISA Kits (7)

Proteins (3)

Type

Custom (2)

Primary (53)

Recombinant (3)

Sandwich (4)

Sandwich CLIA (1)

Target

TYK2 (63)

Reactivity

Human (49)

Mouse (16)

Rat (4)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Horse (3)

Monkey (5)

Xenopus (3)

Application

IHC (16)

IHC-P (4)

WB (36)

ELISA (25)

ICC (1)

IF (6)

IP (1)

Peptide-ELISA (3)

Host

rabbit (48)

mouse (5)

Product Group

IHCPlus (2)

Isotype

IgG (26)

IgG1 (2)

IgG2a,k (3)

Clonality

monoclonal mc (5)

polyclonal pc (48)

Clone

5A4 (1)

6G12 (1)

6H1 (1)

8G8E9, 8G9H5 (1)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (1)

96-Well Strip Plate (5)

APC (2)

APC Conjugated (4)

Azide-free (2)

Biotin Conjugated (6)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (6)

HRP Conjugated (6)

PE Conjugated (4)

Unconjugated (23)

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Epitope

aa667-914 (8)

aa915-1173 (8)

C-Terminus (6)

N-Terminus (6)

aa1021-1070 (4)

980-1060 aa (1)

Val1048 (1)

aa250-299 (1)

aa680-1187 (1)

pTyr1054/1055 (1)

pTyr1054/Tyr1055 (1)

pTyr292 (1)

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Publications

No (63)

Sample Type

Cell Culture Supernatants (1)

Cell Lysates (1)

Plasma (3)

Serum (3)

Tissue Homogenates (2)

Tag

GST, N-terminus (1)

His-T7 (2)

Species

Human (2)

Mouse (1)

Source

E. coli (2)

Wheat Germ Extract (1)

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TYK2 Antibody (clone 6G12) LS-C133500

Antibody:

TYK2 Mouse anti-Human Monoclonal (6G12) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IP, WB

Format:

Unconjugated

Price:

100 µg/$423

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TYK2 Antibody (clone 6H1) LS-C133502

Antibody:

TYK2 Mouse anti-Human Monoclonal (6H1) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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Human TYK2 (Sandwich ELISA) ELISA Kit - LS-F4803

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$798

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TYK2 Antibody LS-C331920

Antibody:

TYK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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TYK2 Antibody (phospho-Tyr1054/Tyr1055) LS-C10925

Antibody:

TYK2 Rabbit anti-Human Polyclonal (pTyr1054/Tyr1055) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$689

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IHC-plus™ TYK2 Antibody LS-B10071

(4.0) Rating

Antibody:

TYK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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Human TYK2 (CLIA) ELISA Kit - LS-F30032

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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IHC-plus™ TYK2 Antibody (Val1048) LS-B9432

(4.0) Rating

Antibody:

TYK2 Rabbit anti-Human Polyclonal (Val1048) Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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TYK2 Antibody LS-C682268

Antibody:

TYK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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TYK2 Antibody (980-1060 aa) LS-C386561

Antibody:

TYK2 Rabbit anti-Human Polyclonal (980-1060 aa) Antibody

Reactivity:

Mouse, Human, Monkey

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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TYK2 Antibody (clone 5A4) LS-C133501

Antibody:

TYK2 Mouse anti-Human Monoclonal (5A4) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$423

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TYK2 Antibody LS-C801338

Antibody:

TYK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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TYK2 Antibody (N-Terminus) LS-C328982

Antibody:

TYK2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

200 µl/$734

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TYK2 Antibody (N-Terminus, Biotin) LS-C283884

Antibody:

TYK2 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Biotin Conjugated

Price:

200 µl/$952

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TYK2 Antibody (N-Terminus, FITC) LS-C283885

Antibody:

TYK2 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

FITC Conjugated

Price:

200 µl/$952

Select

TYK2 Antibody (N-Terminus, PE) LS-C283887

Antibody:

TYK2 Rabbit anti-Human Polyclonal (N-Terminus) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

PE Conjugated

Price:

200 µl/$952

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TYK2 Antibody (N-Terminus, APC) LS-C283883

Antibody:

TYK2 Rabbit anti-Human Polyclonal (N-Terminus) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

APC Conjugated

Price:

200 µl/$952

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TYK2 Antibody (N-Terminus, Azide-free, HRP) LS-C283886

Antibody:

TYK2 Rabbit anti-Human Polyclonal (N-Terminus) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• PE
• APC
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • PE
  • APC
  • HRP, Azide-free

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TYK2 Antibody (C-Terminus) LS-C328984

Antibody:

TYK2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

200 µl/$734

Select

TYK2 Antibody (C-Terminus, FITC) LS-C283890

Antibody:

TYK2 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

FITC Conjugated

Price:

200 µl/$952

Select

TYK2 Antibody (C-Terminus, APC) LS-C283888

Antibody:

TYK2 Rabbit anti-Human Polyclonal (C-Terminus) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

APC Conjugated

Price:

200 µl/$952

• Unconjugated
• FITC
• APC

• Unconjugated
• FITC
• APC

Select

TYK2 Antibody (clone 8G8E9, 8G9H5) LS-C47186

Antibody:

TYK2 Mouse anti-Human Monoclonal (8G8E9, 8G9H5) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

0.1 ml/$419

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TYK2 Antibody (phospho-Tyr292) LS-C291535

Antibody:

TYK2 Rabbit anti-Human Polyclonal (pTyr292) Antibody

Reactivity:

Human

Applications:

ELISA, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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TYK2 Antibody LS-C812859

Antibody:

TYK2 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$332; 100 µg/$404; 200 µg/$505

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TYK2 Antibody (aa680-1187) LS-C185576

Antibody:

TYK2 Rabbit anti-Human Polyclonal (aa680-1187) Antibody

Reactivity:

Human

Applications:

ICC, WB

Format:

Unconjugated

Price:

100 µl/$450

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