Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal (IgG) to Rat TUBB3 / Tubulin Beta 3
IHC - Paraffin, Western blot
Mouse Monoclonal [clone TU-20] (IgG1) to Human TUBB3 / Tubulin Beta 3
Human TUBB3 / Tubulin Beta 3
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [TU-20]
Specificity and Use
Peptide (C) 441-448 coupled to maleimide-activated keyhole limpet hemocyanin via cysteine added to the N-terminus of the neuron-specific peptide.
Recognizes C-terminal peptide sequence ESESQGPK (aa 441-448) of neuron-specific human betaIII-tubulin
Immunocytochemistry on fixed and permeabilized cells. Suggested working dilution is 1:40. The conjugate was also successfully used on paraffin sections using confocal microscopy. It is recommended that the user titrates the reagent for use in the particul The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
TUBB3 Antibody, CDCBM Antibody, Beta III Tubulin Antibody, Class III beta-tubulin Antibody, TUBB4 Antibody, Tubulin, beta 3 Antibody, Tubulin beta-III Antibody, Tubulin beta-3 chain Antibody, Tubulin beta-4 chain Antibody, Tubulin, beta 3 class III Antibody, CFEOM3A Antibody
TUBB3 / Tubulin Beta 3 is a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants.