Pig TUBB / Beta Tubulin

Mouse

Pig (tested or 100% immunogen sequence identity)

IgM Monoclonal

TU-13

Unconjugated

Ion exchange chromatography

Unmodified

Tubulin beta from porcine brain. (N-TERMINAL).

N-Terminus

Recognizes an epitope within the N-terminal region (NT) of tubulin beta, a 50kD globular protein and major constituent of microtubules within the cytoskeleton, involved in meiosis, mitosis, intracellular transport and maintaining cell shape. The evolutionarily conserved heterodimer tubulin, made up of a tubulin alpha and beta chain, binds two molecules of GTP, one at a non-exchangeable site on the alpha chain and one at an exchangeable site on the beta chain. Only the beta chain possesses GTPase activity however, hydrolyzing GTP to GDP, and influencing the stability of the dimer within the microtubule. Clone TU-13 is reported to partially inhibit microtubule assembly in vitro. Is reported as suitable for use in immunocytochemistry.

• IHC - Frozen
• Western blot (1 µg/ml)
• ELISA

Western Blot: LS-C45033 detects a band of approximately 50kD in human RAJI and mouse EL4°Cell lysates.

PBS, 0.09% Sodium Azide

Store at 4°C. Do not freeze. Store undiluted. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P07437 NCBI: NM_178014 NP_821133.1