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Catalog Number	Size	Price
LS-B3442-50	50 µl (0.2 mg/ml)	$565

TUBB / Beta Tubulin Antibody - Anti-TUBB / Tubulin, Beta antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

TUBB / Beta Tubulin Antibody - Anti-TUBB / Tubulin, Beta antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

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PathPlus™ Monoclonal Mouse anti‑Human TUBB / Beta Tubulin Antibody (IHC, IF, WB) LS‑B3442

Name: PathPlus™ TUBB / Beta Tubulin Monoclonal Antibody Mouse IF,IHC,WB | LSBio
Brand: Lifespan BioSciences
SKU: LS-B3442-50
Price: 565.0000 USD
Availability: InStock
Rating: 5 (1 reviews)

Neuroscience

(5.0) Rating

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Note: This antibody replaces LS-C39979

Antibody:

TUBB / Beta Tubulin Mouse anti-Human Monoclonal Antibody

Application:

IHC, IHC-P, IF, WB

Reactivity:

Human, Mouse, Rat, Bovine, Rabbit, Chicken, Frog

Format:

Unconjugated, Unmodified

$565

LS-B3442-50

Toll Free North America

206-374-1102

For Research Use Only

Specifications Validation Publications Reviews Featured Products Request SDS/MSDS

Overview

Antibody:

TUBB / Beta Tubulin Mouse anti-Human Monoclonal Antibody

Application:

IHC, IHC-P, IF, WB

Reactivity:

Human, Mouse, Rat, Bovine, Rabbit, Chicken, Frog

Format:

Unconjugated, Unmodified

Specifications

Description

TUBB (beta tubulin class I) is protein that forms a dimer with alpha tubulin to act as a major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain (TUBB) and one at a non-exchangeable site on the alpha chain. Inherited TUBB mutations lead to development brain defects including cortical dysplasia, while somatic mutations are correlated with drug resistance in cancer. In immunohistochemistry, TUBB has variable degrees of cytoplasmic positivity in all tissues. References: Hum Genet. 1994 Jan;93(1):42-6, PMID: 8270253; Biochem Biophys Res Commun. 2016 Aug 5;476(4):273-279, PMID: 27233604; J Biomol Struct Dyn. 2015;33(12):2530-40, PMID: 26081685; Mol Cancer Ther. 2011 Aug;10(8):1419-29, PMID: 21653684

Target

Human TUBB / Beta Tubulin

Synonyms

See All TUBB / Beta Tubulin Antibodies

Host

Mouse

Reactivity

Human, Mouse, Rat, Bovine, Rabbit, Chicken, Frog (tested or 100% immunogen sequence identity)

Clonality

IgG3 Monoclonal

Conjugations

Unconjugated

Purification

Protein G purified

Modifications

Unmodified

Immunogen

Purified tubulin, 55kD. Cellular Localization: Cytoplasmic

Specificity

Recognizes human Tubulin, beta. Species cross-reactivity: Bovine, rabbit, mouse, chicken, rat, frog, moth and wheat.

Applications

IHC
IHC - Paraffin (10 µg/ml)
Immunofluorescence
Western blot (0.5 - 1 µg/ml)

Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.

Usage

Immunohistochemistry: LS-B3442 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. Western Blot: 0.5-1 ug/ml for 2 hours at RT.

Presentation

PBS, pH 7.4, 0.09% Sodium Azide, 0.2% BSA

Storage

Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.

Restrictions

For research use only. Intended for use by laboratory professionals.

Guarantee

This antibody carries the LSBio 100% Guarantee.

LSBio Guarantee

About TUBB / Beta Tubulin

Uniprot: P07437 NCBI: NM_178014 NP_821133.1

Validation

Anti-TUBB / Tubulin, Beta antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

Anti-TUBB / Tubulin, Beta antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

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PathPlus™ Validation Process