Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
TSSC1 has been reported in PMID 9403053 as one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alignment of this gene to genomic sequence data suggests that this gene resides on chromosome 2 rather than chromosome 11.
Immunofluorescence of monoclonal antibody to TSSC1 on HeLa cell. [antibody concentration 10 ug/ml]
Western Blot analysis of TSSC1 expression in transfected 293T cell line by TSSC1 monoclonal antibody (M01), clone 2H5.Lane 1: TSSC1 transfected lysate (Predicted MW: 43.6 KDa).Lane 2: Non-transfected lysate.
TSSC1 monoclonal antibody (M01), clone 2H5 Western Blot analysis of TSSC1 expression in PC-12.
Enzyme-Linked Immunosorbent Assay
Detection limit for recombinant GST tagged TSSC1 is approximately 1 ng/ml as a capture antibody.
Requested From: United States
Date Requested: 12/9/2016