TSPAN12

tetraspanin 12

Regulator of cell surface receptor signal transduction. Plays a central role in retinal vascularization by regulating norrin (NDP) signal transduction. Acts in concert with norrin (NDP) to promote FZD4 multimerization and subsequent activation of FZD4, leading to promote accumulation of beta-catenin (CTNNB1) and stimulate LEF/TCF-mediated transcriptional programs. Suprisingly, it only activate the norrin (NDP)-dependent activation of FZD4, while it does not activate the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1) (By similarity). Acts as a regulator of membrane proteinases such as ADAM10 and MMP14/MT1-MMP. Activates ADAM10-dependent cleavage activity of amyloid precursor protein (APP). Activates MMP14/MT1-MMP-dependent cleavage activity.

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Products

Antibodies (21)

Proteins (3)

Type

Over-Expression Lysate (2)

Primary (21)

Recombinant (1)

Target

TSPAN12 (24)

Reactivity

Human (21)

Mouse (6)

Rat (6)

Bat (6)

Bovine (6)

Chimpanzee (6)

Dog (6)

Gibbon (6)

Guinea pig (6)

Horse (6)

Monkey (6)

Orangutan (6)

Pig (6)

Rabbit (6)

Zebrafish (3)

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Application

IHC (7)

IHC-P (7)

WB (17)

Flo (1)

ELISA (12)

IF (1)

Host

rabbit (21)

Product Group

IHCPlus (1)

Isotype

IgG (15)

Clonality

polyclonal pc (21)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (4)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (1)

Unconjugated (7)

Epitope

aa232-259 (7)

aa179-228 (4)

aa185-234 (4)

Publications

No (23)

Yes (1)

Tag

Myc-DDK (Flag) (3)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (2)

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TSPAN12 Antibody (aa185-234) LS-B9720

(4.0) Rating

(1) Publication(s)

Antibody:

TSPAN12 Rabbit anti-Human Polyclonal (aa185-234) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

Select

TSPAN12 Antibody (aa185-234, HRP) LS-C449406

Antibody:

TSPAN12 Rabbit anti-Human Polyclonal (aa185-234) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

TSPAN12 Antibody (aa185-234, Biotin) LS-C449404

Antibody:

TSPAN12 Rabbit anti-Human Polyclonal (aa185-234) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

TSPAN12 Antibody (aa185-234, FITC) LS-C449405

Antibody:

TSPAN12 Rabbit anti-Human Polyclonal (aa185-234) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

TSPAN12 Antibody (aa232-259) LS-C160262

Antibody:

TSPAN12 Rabbit anti-Human Polyclonal (aa232-259) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

TSPAN12 Antibody LS-C662792

Antibody:

TSPAN12 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

TSPAN12 Antibody LS-C681623

Antibody:

TSPAN12 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

TSPAN12 Antibody (HRP) LS-C681626

Antibody:

TSPAN12 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

TSPAN12 Antibody (Biotin) LS-C681625

Antibody:

TSPAN12 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

TSPAN12 Antibody (FITC) LS-C681627

Antibody:

TSPAN12 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

TSPAN12 Antibody LS-C661310

Antibody:

TSPAN12 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

TSPAN12 Antibody (aa232-259) LS-C328870

Antibody:

TSPAN12 Rabbit anti-Human Polyclonal (aa232-259) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

TSPAN12 Antibody (aa232-259, Biotin) LS-C246141

Antibody:

TSPAN12 Rabbit anti-Human Polyclonal (aa232-259) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

TSPAN12 Antibody (aa232-259, FITC) LS-C246142

Antibody:

TSPAN12 Rabbit anti-Human Polyclonal (aa232-259) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

TSPAN12 Antibody (aa232-259, Azide-free, HRP) LS-C247925

Antibody:

TSPAN12 Rabbit anti-Human Polyclonal (aa232-259) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

TSPAN12 Antibody (aa232-259, APC) LS-C246477

Antibody:

TSPAN12 Rabbit anti-Human Polyclonal (aa232-259) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

TSPAN12 Antibody (aa232-259, PE) LS-C246144

Antibody:

TSPAN12 Rabbit anti-Human Polyclonal (aa232-259) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• HRP, Azide-free
• APC
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • HRP, Azide-free
  • APC
  • PE

Select

TSPAN12 Antibody (aa179-228) LS-C111131

Antibody:

TSPAN12 Rabbit anti-Human Polyclonal (aa179-228) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

TSPAN12 Antibody (aa179-228, HRP) LS-C449409

Antibody:

TSPAN12 Rabbit anti-Human Polyclonal (aa179-228) (HRP) Antibody

Reactivity:

Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Bat, Rat, Gibbon, Human, Monkey, Orangutan, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

TSPAN12 Antibody (aa179-228, Biotin) LS-C449407

Antibody:

TSPAN12 Rabbit anti-Human Polyclonal (aa179-228) (Biotin) Antibody

Reactivity:

Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Bat, Rat, Gibbon, Human, Monkey, Orangutan, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

TSPAN12 Antibody (aa179-228, FITC) LS-C449408

Antibody:

TSPAN12 Rabbit anti-Human Polyclonal (aa179-228) (FITC) Antibody

Reactivity:

Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Bat, Rat, Gibbon, Human, Monkey, Orangutan, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

Human TSPAN12 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89725

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.2 kDa

Price:

20 µg/$150

Select

Human TSPAN12 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71423

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.2 kDa

Price:

20 µg/$1,107

Select

TSPAN12 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101085

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.2 kDa

Price:

100 µg/$494

Viewing 1-24 of 24 product results

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