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Anti-TSH Receptor / TSHR Antibody (aa101-115) LS-C154893

Ordering

Wt. Vol. Conc. Price
100 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular TSH Receptor / TSHR Antibodies

Anti-TSH Receptor / TSHR Antibody (C-Terminus) IHC-plus™ LS-A1449
Rabbit Polyclonal to Human TSH Receptor / TSHR
Human
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-TSH Receptor / TSHR Antibody (N-Terminus) IHC-plus™ LS-A1446
Rabbit Polyclonal to Human TSH Receptor / TSHR
Human
IHC - Paraffin
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Goat Polyclonal to Human TSH Receptor / TSHR
Human
Western blot, ELISA
Unconjugated

Details

Human TSH Receptor / TSHR
Goat
Human (tested or 100% immunogen sequence identity)
Monkey, Bovine, Sheep (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • Western blot (0.5 - 2 µg/ml)
  • ELISA (1:16000)

Specificity and Use

TSH Receptor / TSHR antibody was raised against synthetic peptide C-SKVTHIEIRNTRNLT from an internal region of human TSH Receptor (NP_000360.2; NP_001018046.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon (100%); Monkey, Marmoset, Sheep, Bovine (93%); Galago, Mouse, Rat, Elephant, Panda, Bat, Dog, Feline, Horse, Rabbit, Porcine, Opossum, Guinea pig, Turkey, Zebra finch, Chicken (87%).
LS-E27765 - Lyophilized - 100 µg - $145.00
aa101-115
Human TSH Receptor. This antibody is expected to recognize reported isoform 1 (NP_000360.2) and isoform 2 (NP_001018046.1). The immunizing peptide sequence corresponds to a part of the extracellular domain.
Peptide ELISA: antibody detection limit dilution 1:16000. Western blot: Approx 28kD band observed in Human Thyroid Gland lysates (calculated MW of 28.4kD according to NP_001018046.1). Recommended concentration: 0.5-2 ug/ml.

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About TSH Receptor / TSHR

P16473 NM_000369 NP_000360.2

TSHR Antibody, CHNG1 Antibody, HTSHR-I Antibody, LGR3 Antibody, Thyrotrophin receptor Antibody, TSH-R Antibody, TSH receptor Antibody, Thyrotropin receptor Antibody

Thyrotropin Receptor, a Glycoprotein Hormone Receptor, plays a central role in controlling thyroid cell metabolism. The TSH receptor can interact with both TSH and autoantibodies against the TSH receptor (thyroid-stimulating immunoglobulins, TSI). Mutations in the receptor are the cause for hyperthyroidism such as gestational hyperthyroidism (hypersensitivity to chorionic gonadotropin) and Grave's disease (autoimmune hyperthyroidism).

Western blot

Western blot
TSHR antibody (0.5 ug/ml) staining of Human Thyroid gland lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
 

Requested From: United States
Date Requested: 12/8/2016

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