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TSG101
tumor susceptibility 101
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses.
| Gene Name: | tumor susceptibility 101 |
| Synonyms: | TSG101, ESCRT-I complex subunit TSG101, Tumor susceptibility gene 10, Tumor susceptibility protein, VPS23, Tumor susceptibility gene 101, TSG10 |
| Target Sequences: | NM_006292 NP_006283.1 Q99816 |
Publications (4)
1
A Refined Bead-Free Method to Identify Astrocytic Exosomes in Primary Glial Cultures and Blood Plasma. Willis CM, Ménoret A, Jellison ER, Nicaise AM, Vella AT, Crocker SJ. Frontiers in neuroscience. 2017 11:335. (IHC; Human)
[Full Text Article]
[PubMed:28663721]
Related Antibodies: LS-C539950.
2
Exosomes From Human Cardiac Progenitor Cells for Therapeutic Applications: Development of a GMP-Grade Manufacturing Method. Andriolo G, Provasi E, Lo Cicero V, Brambilla A, Soncin S, Torre T, Milano G, Biemmi V, Vassalli G, Turchetto L, Barile L, Radrizzani M. Frontiers in physiology. 2018 August;9:1169. [Full Text Article]
[PubMed:30197601]
[PMC:PMC6117231]
3
Cancer-derived small extracellular vesicles promote angiogenesis by heparin-bound, bevacizumab-insensitive VEGF, independent of vesicle uptake. Ko SY, Lee W, Kenny HA, Dang LH, Ellis LM, Jonasch E, Lengyel E, Naora H. Communications biology. 2019 October;2: [Full Text Article]
[PubMed:31646189]
[PMC:PMC6802217]
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TSG101
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(3)
TSG101 Mouse anti-Human Monoclonal (5B7) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$834
TSG101 Rabbit anti-Mouse Polyclonal (aa121-170) (Biotin) Antibody
Rabbit, Mouse, Dog, Rat, Horse, Human
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$442
TSG101 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rat, Human
WB
Unconjugated
100 µl/$397
TSG101 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, IF, IHC, WB
Biotin Conjugated
100 µl/$904
TSG101 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, IF, IHC, WB
FITC Conjugated
100 µl/$904
TSG101 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, IF, IHC, WB
APC Conjugated
100 µl/$904
TSG101 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, IF, IHC, WB
PE Conjugated
100 µl/$904
TSG101 Rabbit anti-Mouse Polyclonal (aa164-213) Antibody
Mouse
WB
Unconjugated
100 µl/$397
TSG101 Mouse anti-Human Monoclonal (aa167-374) (4A10) Antibody
Mouse, Human
IF, IHC, IP, WB
Unconjugated
100 µl/$450
TSG101 Rabbit anti-Human Polyclonal (aa281-330) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
TSG101 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
TSG101 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
TSG101 Rabbit anti-Human Polyclonal (aa361-390) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Rat, Hamster, Bat, Sheep, Bovine, Rabbit, Mouse, Goat, Dog, Guinea pig, Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
TSG101 Rabbit anti-Human Polyclonal (250-330 aa, C-terminal) Antibody
Mouse, Rat, Human, Monkey
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
TSG101 Rabbit anti-Human Polyclonal (aa340-370) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
TSG101 Rabbit anti-Human Polyclonal Antibody
Rat, Human
WB
Unconjugated
100 µg/$575
TSG101 Rabbit anti-Human Polyclonal (aa225-275) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
TSG101 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
TSG101 Rabbit anti-Human Polyclonal (Glu303) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
TSG101 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ICC, IF, IP, WB
Unconjugated, Preservative Free
20 µl/$271; 100 µl/$412
TSG101 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
TSG101 Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
TSG101 Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
TSG101 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
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