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Anti-TSC22D3 / GILZ Antibody (clone CFMKG15) LS-C106408

Ordering

Wt. Vol. Conc. Price
25 µg - 0.5 mg/ml $225
100 µg - 0.5 mg/ml $345
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
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Most Popular TSC22D3 / GILZ Antibodies

Anti-TSC22D3 / GILZ Antibody (clone 3A5) IHC-plus™ LS-B4313
Mouse Monoclonal [clone 3A5] (IgG1,k) to Human TSC22D3 / GILZ
Human
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-TSC22D3 / GILZ Antibody (clone 1E11) LS-C174291
Mouse Monoclonal [clone 1E11] (IgG1) to Human TSC22D3 / GILZ
Human
Immunofluorescence, Western blot
Unconjugated
Immunofluorescence Image

100% Guaranteed 100% Guaranteed
Rat Monoclonal [clone CFMKG15] (IgG2a,k) to Mouse TSC22D3 / GILZ
Mouse, Human
Western blot
Unconjugated

Details

Mouse TSC22D3 / GILZ
Rat
Mouse, Human (tested or 100% immunogen sequence identity)
IgG2a,k Monoclonal [CFMKG15]
Unconjugated
Affinity purified
Unmodified

Applications

Western blot

Specificity and Use

TSC22D3 / GILZ antibody was raised against mouse TSC22D3
This CFMKG15 antibody has been tested by western blot analysis of dexamethasone-treated mouse thymocytes. CFMKG15 recognizes endogenous mouse GILZ with an approximate molecular weight of 14 kD; a non-specific band of approximately 95 kD is also observed. CFMKG15 also recognizes endogenous human GILZ in dexamethasone-treated peripheral blood mononuclear cells, with an approximate molecular weight of 14 kD; non-specific bands may also appear at approximately 33 kD and 95 kD. This can be used at less than or equal to 2 ug/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Packaging

PBS, pH 7.2, 150 mM sodium chloride, 0.09% sodium azide
Store at 4°C, avoid repeated freeze thaw cycles.
For research use only.

About TSC22D3 / GILZ

Q99576 NM_004089 NP_004080.2

TSC22D3 Antibody, DSIPI Antibody, DIP Antibody, DSIP-immunoreactive peptide Antibody, GILZ Antibody, TSC-22 related protein Antibody, Protein DIP Antibody, TSC22 domain family protein 3 Antibody, HDIP Antibody, TSC-22-like protein Antibody, TSC-22-related protein Antibody, TSC-22R Antibody, TSC22 domain family, member 3 Antibody

Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities (By similarity).

Western blot

Western blot
Western Blot of human PBMC cultured without (lane 1) or with (lane 2) dexamethasone (10-7 M) for 3 hr. The membrane was probed with 2 ug/mL anti-mouse/human GILZ (CFMKG15), followed by HRP-conjugated anti-rat IgG.

Western blot

Western blot
Western Blot of mouse thymocytes cultured without (lane 1) or with (lane 2) dexamethasone (10-7 M) for 3 hr. The membrane was probed with 10 ug/mL anti-mouse/human GILZ (CFMKG15), followed by HRP-conjugated anti-rat IgG.

Requested From: United States
Date Requested: 12/8/2016

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