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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TS / Thymidylate Synthase Antibody (clone TS 106) LS‑C45497
Antibody
Thymidylate Synthase antibody LS-C45497 is an unconjugated mouse monoclonal antibody to human Thymidylate Synthase (TS). Validated for ELISA, Flow, IF, IHC, IP and WB.
Catalog
Size
Price
LS-C45497-100
100 µg
Unavailable

Popular TS / Thymidylate Synthase Products

Antibody
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Anti-TYMS antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1460 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation, ELISA
Anti-TYMS antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6165 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation, ELISA
IHC of paraffin-embedded Human tonsil using anti-TYMS mouse monoclonal antibody.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Detection of Human and Mouse TS by Western Blot. Samples: Whole cell lysate (50 ug) from Jurkat, 293T, HeLa, mouse TCMK-1, and mouse NIH3T3 cells. Antibodies: Affinity purified rabbit anti-TS antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
Species: Human, Mouse, Rat, Bovine, Dog, Pig, Rabbit
Applications: Western blot, Immunoprecipitation

Product Description

Thymidylate Synthase antibody LS-C45497 is an unconjugated mouse monoclonal antibody to human Thymidylate Synthase (TS). Validated for ELISA, Flow, IF, IHC, IP and WB.
About TS / Thymidylate Synthase
Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. P04818 NM_001071 NP_001062.1

TYMS Antibody, HST422 Antibody, Thymidylate synthetase Antibody, TMS Antibody, TS Antibody, Thymidylate synthase Antibody, Tsase Antibody


Specifications

Target
Human TS / Thymidylate Synthase
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [TS 106]
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:50 - 1:100)
  • IHC - Frozen (1:50 - 1:100)
  • Immunofluorescence
  • Western blot (1:200 - 1:400)
  • Immunoprecipitation
  • Flow Cytometry
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Western Blot: LS-C45497 detects a band of approximately 36 kD under reduced conditions.
Presentation
PBS, pH 7.6, 0.09% sodium azide.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/18/2018

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