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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TRXR1 / TXNRD1 Antibody LS‑C189914
Antibody
TXNRD1 antibody LS-C189914 is an unconjugated rabbit polyclonal antibody to human TXNRD1 (TRXR1). Validated for IP and WB.
Catalog
Size
Price
LS-C189914-100
100 µl (0.5 mg/ml)
Unavailable

Popular TRXR1 / TXNRD1 Products

Western blot Image
Species: Human
Applications: Western blot, Immunoprecipitation, ELISA
Anti-TXNRD1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3926 concentration 2.5 ug/ml.
Species: Human, Monkey, Dog, Pig
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
ICC: CMXRos (a mitochondrial marker; 1:8000 dilution; Molecular Probes; red staining) was added to U937 cells growing in suspension, which were then incubated at 37°C for 30 min. Cells were fixed in paraformaldehyde and permeabilized. Cells were then incubated in blocking buffer (5% normal goat serum in PBS plus 0.05% Tween 20), and then in anti-TrxR1 (TrxR1; 1:100 dilution; green staining). After washing, cells were incubated with an anti-rabbit-Alexa 488 secondary antibody conjugate (1:100 dilution; Molecular Probes), washed, mounted in DAPI (blue staining) containing medium, and visualized in an Olympus IX71 confocal fluorescent microscope. Data generously provided by Ismael Samudio, Dept. of Blood and Marrow Transplantation, University of Texas M.D. Anderson Cancer Center.
Species: Human, Monkey, Rat, Bovine, Dog, Guinea pig, Pig
Applications: ICC, Western blot
Anti-TRXR1 / TXNRD1 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7890 dilution 1:200.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human
Applications: IHC, Immunofluorescence, Western blot, Immunoprecipitation, Flow Cytometry, ELISA

Product Description

TXNRD1 antibody LS-C189914 is an unconjugated rabbit polyclonal antibody to human TXNRD1 (TRXR1). Validated for IP and WB.
About TRXR1 / TXNRD1
TRXR1 / TXNRD1 is a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. Q16881 NM_003330 NP_003321.3

TXNRD1 Antibody, GRIM12 Antibody, KDRF Antibody, Oxidoreductase Antibody, TRXR1 Antibody, Thioredoxin reductase GRIM-12 Antibody, Thioredoxin reductase 1 Antibody, TR Antibody, GRIM-12 Antibody, Thioredoxin reductase Antibody, Thioredoxin reductase TR1 Antibody, TR1 Antibody, TXNR Antibody


Specifications

Target
Human TRXR1 / TXNRD1
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Applications
  • Western blot (1:1000 - 1:2000)
  • Immunoprecipitation
Immunogen
TRXR1 / TXNRD1 antibody was raised against recombinant corresponding to human TR1 expressed in E.coli.
Specificity
Human TR1.
Presentation
HEPES, 0.15 M sodium chloride, 0.01% BSA, 0.03% sodium azide, 50% glycerol
Storage
May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/22/2018

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