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Anti-TRXR1 / TXNRD1 Antibody (aa137-150) LS-C152788

Note: This antibody replaces LS-C18077


Wt. Vol. Conc. Price
100 µg - 1 mg/ml $425
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular TRXR1 / TXNRD1 Antibodies

Anti-TRXR1 / TXNRD1 Antibody (aa600-612) IHC-plus™ LS-B3926
Goat Polyclonal to Human TRXR1 / TXNRD1
Human, Monkey, Dog, Pig
IHC - Paraffin, Western blot, ELISA
Immunohistochemistry Image
Anti-TRXR1 / TXNRD1 Antibody (aa137-150) LS-C152788
Rabbit Polyclonal (IgG) to Human TRXR1 / TXNRD1
Human, Monkey, Rat, Bovine, Dog, Guinea pig, Pig
ICC, Western blot
Immunocytochemistry Image
Anti-TRXR1 / TXNRD1 Antibody IHC-plus™ LS-B7890
Rabbit Polyclonal (IgG) to Human TRXR1 / TXNRD1
IHC - Paraffin, Western blot
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human TRXR1 / TXNRD1
Human, Monkey, Rat, Bovine, Dog, Guinea pig, Pig
ICC, Western blot


Human TRXR1 / TXNRD1
Human, Monkey, Rat, Bovine, Dog, Guinea pig, Pig (tested or 100% immunogen sequence identity)
Mouse, Bat, Horse, Rabbit (at least 90% immunogen sequence identity)
IgG Polyclonal
Immunoaffinity purified


  • ICC
  • Western blot

Specificity and Use

TRXR1 / TXNRD1 antibody was raised against peptide corresponding to amino acids 137-150 (C-PHRIKATNNKGKEK) of human thioredoxin reductase 1 Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Panda, Dog, Bovine, Pig, Guinea pig (100%); Mouse, Elephant, Bat, Rabbit, Horse, Opossum (93%); Rat (86%).
Thioredoxin reductase 1


0.1 M Tris-glycine, pH 7.4, 0.15 M sodium chloride, 0.05% sodium azide, 30% glycerol
Store at -20°C.
For research use only.

About TRXR1 / TXNRD1

Q16881 NM_003330 NP_003321.3

TXNRD1 Antibody, GRIM12 Antibody, KDRF Antibody, Oxidoreductase Antibody, TRXR1 Antibody, Thioredoxin reductase GRIM-12 Antibody, Thioredoxin reductase 1 Antibody, TR Antibody, GRIM-12 Antibody, Thioredoxin reductase Antibody, Thioredoxin reductase TR1 Antibody, TR1 Antibody, TXNR Antibody

TRXR1 / TXNRD1 is a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination.


ICC: CMXRos (a mitochondrial marker; 1:8000 dilution; Molecular Probes; red staining) was added to U937 cells growing in suspension, which were then incubated at 37°C for 30 min. Cells were fixed in paraformaldehyde and permeabilized. Cells were then incubated in blocking buffer (5% normal goat serum in PBS plus 0.05% Tween 20), and then in anti-TrxR1 (TrxR1; 1:100 dilution; green staining). After washing, cells were incubated with an anti-rabbit-Alexa 488 secondary antibody conjugate (1:100 dilution; Molecular Probes), washed, mounted in DAPI (blue staining) containing medium, and visualized in an Olympus IX71 confocal fluorescent microscope. Data generously provided by Ismael Samudio, Dept. of Blood and Marrow Transplantation, University of Texas M.D. Anderson Cancer Center.

Western blot

Western blot
WB: 40 micrograms of rat brain microsomal preparation was probed with anti-Thioredoxin Reductase 1 (1g/ml)

Requested From: United States
Date Requested: 10/24/2016

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