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TRXR1 / TXNRD1

thioredoxin reductase 1

TRXR1 / TXNRD1 is a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.

Gene Name: thioredoxin reductase 1
Synonyms: TXNRD1, GRIM12, KDRF, Oxidoreductase, TRXR1, Thioredoxin reductase GRIM-12, Thioredoxin reductase 1, TR, GRIM-12, Thioredoxin reductase, Thioredoxin reductase TR1, TR1, TXNR
Target Sequences: NM_003330 NP_003321.3 Q16881

☰ Filters
Antibodies (44)
ELISA Kits (23)
Proteins (9)
Custom (4)
Primary (44)
Recombinant (9)
Sandwich (15)
Sandwich CLIA (4)
TRXR1 / TXNRD1 (76)
Human (42)
Mouse (30)
Rat (21)
Chicken (1)
Dog (1)
Guinea pig (1)
Monkey (2)
Pig (2)
Porcine (1)
Rabbit (1)
IHC (6)
IHC-P (3)
WB (33)
Flo (3)
ELISA (11)
ICC (3)
IF (4)
IP (3)
Peptide-ELISA (2)
rabbit (33)
mouse (10)
goat (1)
Product Group
IHCPlus (2)
Ig (2)
IgG (10)
IgG1 (7)
IgG1,k (1)
IgG2b,k (1)
monoclonal mc (10)
polyclonal pc (34)
06 (1)
AT30F1 (1)
OTI3E1 (2)
OTI5G3 (2)
OTI7B2 (2)
12 x 8-Well Microstrips (2)
96-Well Microplate (4)
96-Well Strip Plate (17)
APC (2)
APC Conjugated (2)
Biotin Conjugated (4)
Carrier-free (3)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (4)
HRP Conjugated (3)
PE Conjugated (2)
Preservative Free (1)
Unconjugated (25)
aa208-433 (8)
aa374-577 (8)
aa1-497 (4)
C-Terminus (1)
Internal (1)
aa125-175 (1)
aa600-612 (1)
No (76)
Plasma (15)
Serum (15)
Tissue Homogenates (6)
GST (1)
His (3)
His, N-Terminal (1)
His-SUMO (1)
His-T7 (2)
Myc-DDK (Flag) (1)
Human (7)
Mouse (1)
Rat (1)
E. coli (7)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (3)
Biologically active (1)
TRXR1 / TXNRD1 Antibody - Anti-TXNRD1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
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TRXR1 / TXNRD1 Goat anti-Human Polyclonal (aa600-612) Antibody
Dog, Pig, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
TRXR1 / TXNRD1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$782
TRXR1 / TXNRD1 Protein
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E. coli
His
Biologically active
100 µg/$342; 20 µg/$254
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TRXR1 / TXNRD1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IF, IHC, IP, WB
Unconjugated
100 µg/$341
TRXR1 / TXNRD1 Antibody - Anti-TRXR1 / TXNRD1 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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TRXR1 / TXNRD1 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
TRXR1 / TXNRD1 Antibody - ICC/IF analysis of TXNRD1 in Hep3B cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human TXNRD1 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).ICC/IF analysis of TXNRD1 in A549 cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human TXNRD1 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
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TRXR1 / TXNRD1 Mouse anti-Human Monoclonal (AT30F1) Antibody
Human
ELISA, Flo, ICC, WB
Unconjugated
50 µl/$303; 100 µl/$365
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TRXR1 / TXNRD1 Mouse anti-Human Monoclonal (Preservative Free) (06) Antibody
Human
Flo, ICC, IF
Unconjugated, Preservative Free
100 µl/$412
TRXR1 / TXNRD1 Antibody - Immunohistochemistry of paraffin-embedded Human placenta using TXNRD1 Polyclonal Antibody at dilution of 1:100 (40x lens).
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TRXR1 / TXNRD1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
TRXR1 / TXNRD1 Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-TXNRD1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:2000)
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TRXR1 / TXNRD1 Mouse anti-Human Monoclonal (OTI7B2) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µl/$434
TRXR1 / TXNRD1 Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-TXNRD1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:2000)
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TRXR1 / TXNRD1 Mouse anti-Human Monoclonal (Carrier-free) (OTI7B2) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
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TRXR1 / TXNRD1 Mouse anti-Human Monoclonal Antibody
Human
ICC, IF
Unconjugated
100 µl/$412
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TRXR1 / TXNRD1 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IP
Unconjugated
100 µg/$562
TRXR1 / TXNRD1 Antibody - All lanes: Anti-TXNRD1 Antibody (C-Term) at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: Neuro-2a whole cell lysate Lane 3: NIH/3T3 whole cell lysate Lane 4: PC-3 whole cell lysate Lane 5: human testis lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 71 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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TRXR1 / TXNRD1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$393
TRXR1 / TXNRD1 Antibody - Anti-TXNRD1 Antibody (Center) at 1:2000 dilution + PC-3 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 71 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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TRXR1 / TXNRD1 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$393
TRXR1 / TXNRD1 Antibody - Western blot of recombinant TRXR1 / TXNRD1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TRXR1 / TXNRD1 Rabbit anti-Mouse Polyclonal (aa374-577) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161
TRXR1 / TXNRD1 Antibody - Western blot of recombinant TRXR1 / TXNRD1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TRXR1 / TXNRD1 Rabbit anti-Mouse Polyclonal (aa374-577) (HRP) Antibody
Mouse, Human
WB
HRP Conjugated
100 µl/$329; 200 µl/$379; 500 µl/$547; 1 ml/$649; 2 ml/$884; 5 ml/$1,475
TRXR1 / TXNRD1 Antibody - Western blot of recombinant TRXR1 / TXNRD1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TRXR1 / TXNRD1 Rabbit anti-Mouse Polyclonal (aa374-577) (Biotin) Antibody
Mouse, Human
WB
Biotin Conjugated
100 µl/$311; 200 µl/$353; 500 µl/$496; 1 ml/$567; 2 ml/$769; 5 ml/$1,248
TRXR1 / TXNRD1 Antibody - Western blot of recombinant TRXR1 / TXNRD1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TRXR1 / TXNRD1 Rabbit anti-Mouse Polyclonal (aa374-577) (FITC) Antibody
Mouse, Human
WB
FITC Conjugated
100 µl/$338; 200 µl/$392; 500 µl/$573; 1 ml/$698; 2 ml/$936; 5 ml/$1,588
TRXR1 / TXNRD1 Antibody - Western blot of recombinant TRXR1 / TXNRD1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TRXR1 / TXNRD1 Rabbit anti-Mouse Polyclonal (aa374-577) (APC, Cy7) Antibody
Mouse, Human
WB
APC, Cy7 Conjugated
100 µl/$483; 200 µl/$599; 500 µl/$1,089; 1 ml/$1,297; 2 ml/$1,815; 5 ml/$3,403
TRXR1 / TXNRD1 Antibody - Western blot of recombinant TRXR1 / TXNRD1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TRXR1 / TXNRD1 Rabbit anti-Mouse Polyclonal (aa374-577) (Cy3) Antibody
Mouse, Human
WB
Cy3 Conjugated
100 µl/$392; 200 µl/$470; 500 µl/$798; 1 ml/$951; 2 ml/$1,211; 5 ml/$2,269
TRXR1 / TXNRD1 Antibody - Western blot of recombinant TRXR1 / TXNRD1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
TRXR1 / TXNRD1 Rabbit anti-Mouse Polyclonal (aa374-577) (APC) Antibody
Mouse, Human
WB
APC Conjugated
100 µl/$392; 200 µl/$470; 500 µl/$798; 1 ml/$951; 2 ml/$1,211; 5 ml/$2,269
TRXR1 / TXNRD1 Antibody - Western blot of recombinant TRXR1 / TXNRD1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TRXR1 / TXNRD1 Rabbit anti-Mouse Polyclonal (aa374-577) (PE) Antibody
Mouse, Human
WB
PE Conjugated
100 µl/$392; 200 µl/$470; 500 µl/$798; 1 ml/$951; 2 ml/$1,211; 5 ml/$2,269
TRXR1 / TXNRD1 Antibody - Detection of human Thioredoxin Reductase 1 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-Thioredoxin Reductase 1 antibody used for WB at 0.1 µg/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
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TRXR1 / TXNRD1 Rabbit anti-Human Polyclonal (aa125-175) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
TRXR1 / TXNRD1 Antibody - Immunohistochemistry of paraffin-embedded human liver tissue using TXNRD1 Antibody at dilution of 1:100
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TRXR1 / TXNRD1 Rabbit anti-Human Polyclonal (aa1-497) Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
TRXR1 / TXNRD1 Antibody - Western blot analysis of TXNRD1 using Jurkat whole cells lysates. The lane on the left is treated with the antigen-specific peptide.
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TRXR1 / TXNRD1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Viewing 1-25 of 76 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).