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Anti-TRPV4 Antibody (1st Cytoplasmic Domain) LS-C95200
Most Popular TRPV4 Antibodies
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Details
| Mouse TRPV4 | |
| Sheep | |
| Mouse, Human, Rat (tested or 100% immunogen sequence identity) | |
| IgG Polyclonal | |
| Unconjugated | |
| Purified | |
| Unmodified |
Applications
- IHC
- Western blot
Specificity and Use
| TRPV4 antibody was raised against synthetic peptide from the 1st cytoplasmic loop of mouse TRPV4 conjugated to an immunogenic carrier protein. The antigen is homologous in rat and human. | |
| 1st Cytoplasmic Domain | |
| Specific for TRPV4. | |
| IHC: Antigen retrieval is essential for use on paraffin sections. |
Packaging
| Lyophilized. Centrifuge to remove any insoluble material | |
| 500 µl Sterile water | |
| Maintain lyophilized and reconstituted antibodies at -20°C for long term storage and at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze/thaw cycles. | |
| For research use only. |
About TRPV4
Q9HBA0
NM_021625
NP_067638.3
TRPV4 Antibody, CMT2C Antibody, HMSN2C Antibody, OTRPC4 Antibody, SSQTL1 Antibody, VR-OAC Antibody, VRL-2 Antibody, Osm-9-like TRP channel 4 Antibody, SPSMA Antibody, TRP12 Antibody, VRL2 Antibody, VROAC Antibody, SMAL Antibody
Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca2+ potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism.
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Requested From:
Date Requested: 4/24/2018
Date Requested: 4/24/2018
