TRPM5

transient receptor potential cation channel, subfamily M, member 5

Voltage-modulated Ca2+-activated, monovalent cation channel (VCAM) that mediates a transient membrane depolarization and plays a central role in taste transduction. Monovalent-specific, non-selective cation channel that mediates the transport of Na+, K+ and Cs+ ions equally well. Activated directly by increases in intracellular Ca2+, but is impermeable to it. Gating is voltage-dependent and displays rapid activation and deactivation kinetics upon channel stimulation even during sustained elevations in Ca2+. Also activated by a fast intracellular Ca2+ increase in response to inositol 1,4,5-triphosphate-producing receptor agonists. The channel is blocked by extracellular acidification. External acidification has 2 effects, a fast reversible block of the current and a slower irreversible enhancement of current inactivation. Is a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. Heat activation is due to a shift of the voltage-dependent activation curve to negative potentials. Activated by arachidonic acid in vitro. May be involved in perception of bitter, sweet and umami tastes. May also be involved in sensing semiochemicals.

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Products

Antibodies (14)

Proteins (2)

Type

Over-Expression Lysate (2)

Primary (14)

Target

TRPM5 (16)

Reactivity

Human (13)

Mouse (10)

Rat (8)

Bovine (3)

Gibbon (3)

Guinea pig (6)

Zebrafish (1)

Application

IHC (12)

IHC-P (10)

WB (14)

ELISA (2)

IF (1)

Host

rabbit (13)

rabbit-new zealand white (1)

Product Group

IHCPlus (1)

Isotype

IgG (13)

Clonality

polyclonal pc (14)

Format

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

Unconjugated (8)

Epitope

aa205-254 (4)

aa247-296 (4)

aa1021-1108 (1)

Publications

No (16)

Tag

Myc-DDK (Flag) (2)

Species

Human (1)

Source

293T Cells (1)

HEK 293 Cells (1)

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TRPM5 Antibody (aa247-296) LS-C80116

Antibody:

TRPM5 Rabbit anti-Human Polyclonal (aa247-296) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$397

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TRPM5 Antibody (aa247-296, HRP) LS-C432115

Antibody:

TRPM5 Rabbit anti-Human Polyclonal (aa247-296) (HRP) Antibody

Reactivity:

Mouse, Guinea pig, Bovine, Rat, Gibbon, Human

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$442

Select

TRPM5 Antibody (aa247-296, Biotin) LS-C432418

Antibody:

TRPM5 Rabbit anti-Human Polyclonal (aa247-296) (Biotin) Antibody

Reactivity:

Mouse, Guinea pig, Bovine, Rat, Gibbon, Human

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$442

Select

TRPM5 Antibody (aa247-296, FITC) LS-C432421

Antibody:

TRPM5 Rabbit anti-Human Polyclonal (aa247-296) (FITC) Antibody

Reactivity:

Mouse, Guinea pig, Bovine, Rat, Gibbon, Human

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$442

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

TRPM5 Antibody (aa205-254) LS-B6792

Antibody:

TRPM5 Rabbit anti-Human Polyclonal (aa205-254) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

Select

TRPM5 Antibody (aa205-254, HRP) LS-C432416

Antibody:

TRPM5 Rabbit anti-Human Polyclonal (aa205-254) (HRP) Antibody

Reactivity:

Mouse, Guinea pig, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

TRPM5 Antibody (aa205-254, Biotin) LS-C432415

Antibody:

TRPM5 Rabbit anti-Human Polyclonal (aa205-254) (Biotin) Antibody

Reactivity:

Mouse, Guinea pig, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

TRPM5 Antibody (aa205-254, FITC) LS-C432417

Antibody:

TRPM5 Rabbit anti-Human Polyclonal (aa205-254) (FITC) Antibody

Reactivity:

Mouse, Guinea pig, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

TRPM5 Antibody LS-C490573

Antibody:

TRPM5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$575

Select

Human TRPM5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91377

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

131.3 kDa

Price:

20 µg/$150

Select

TRPM5 Antibody (aa1021-1108) LS-C408115

Antibody:

TRPM5 Rabbit anti-Human Polyclonal (aa1021-1108) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

TRPM5 Antibody LS-C402832

Antibody:

TRPM5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

TRPM5 Antibody LS-C661287

Antibody:

TRPM5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

TRPM5 Antibody LS-C829144

Antibody:

TRPM5 Rabbit-New Zealand White anti-Zebrafish Polyclonal Antibody

Reactivity:

Zebrafish

Applications:

IHC, WB

Format:

Unconjugated

Price:

500 µg/$393

Select

TRPM5 Antibody LS-C747471

Antibody:

TRPM5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

TRPM5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G113864

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

131.3 kDa

Price:

100 µg/$494

Viewing 1-16 of 16 product results

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