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Anti-TRPC6 Antibody (aa832-846) IHC-plus™ LS-B14655

Note: This antibody replaces LS-C155007
Catalog Size Price
LS-B14655-50 50 µg (0.5 mg/ml) Unavailable

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Anti-TRPC6 Antibody (C-Terminus) IHC-plus™ LS-B611
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Anti-TRPC6 Antibody (aa792-841) LS-C109996
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Anti-TRPC6 Antibody (N-Terminus) LS-C112235
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Anti-TRPC6 Antibody (aa249-265) LS-C312900
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100% Guaranteed
Goat Polyclonal to Mouse TRPC6
Mouse, Human
IHC - Paraffin, ELISA


Mouse TRPC6
Mouse, Human (tested or 100% immunogen sequence identity)
Rat (at least 90% immunogen sequence identity)
Immunoaffinity purified


  • IHC - Paraffin (5 µg/ml)
  • ELISA (1:64000)

Specificity and Use

TRPC6 antibody was raised against synthetic peptide C-KQSSTRSSEDYHLNS from an internal region of mouse TRPC6 (NP_038866.2). Percent identity by BLAST analysis: Mouse (100%); Rat (93%); Elephant, Porcine, Opossum, Guinea pig, Platypus (87%); Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Galago, Panda, Dog, Bovine, Horse, Rabbit (80%).
LS-E27885 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B14655. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Mouse TRPC6.
Peptide ELISA: antibody detection limit dilution 1:64000. Western blot: Preliminary experiments gave an approx 75kD band in Mouse and Rat Brain and Spinal Cord lysates after 0.3 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 107kD according to NP_038866.2. The 75kD band was successfully blocked by incubation with the immunizing peptide.


Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About TRPC6

Q9Y210 NM_004621 NP_004612.2

TRPC6 Antibody, Transient receptor protein 6 Antibody, Trrp6 Antibody, TRP-6 Antibody, TRP6 Antibody, FSGS2 Antibody

Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion.

Immunohistochemistry - Paraffin

Immunohistochemistry - Paraffin
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)

Requested From: 
Date Requested: 9/22/2017

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