Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone NDOG1] (IgM) to Human Trophoblast Protein
Human, Cynomolgus monkey
IHC - Frozen, Flow Cytometry
Human Trophoblast Protein
Human, Cynomolgus monkey (tested or 100% immunogen sequence identity)
IgM Monoclonal [NDOG1]
IHC - Frozen (1:1 - 1:10)
Flow Cytometry (1:1 - 1:10)
Specificity and Use
Human trophoblast membranes.
Demonstrates a striking and consistent immunohistological reactivity around sites of trophoblastic invasion in the human placenta. Despite preliminary data suggesting that Recognizes hyaluronic acid, it has not been possible to confirm the precise antigenic reactivity of this reagent. Although the immunohistological staining of placenta is abolished by treatment with hyaluronidase, it has not been possible to demonstrate binding of the antibody to purified hyaluronic acid.