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TRF1 / TERF1
telomeric repeat binding factor (NIMA-interacting) 1
Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded 5'-TTAGGG-3' repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.
| Gene Name: | telomeric repeat binding factor (NIMA-interacting) 1 |
| Synonyms: | TERF1, HTRF1-AS, NIMA-interacting protein 2, PIN2, Telomeric protein Pin2/TRF1, TRBF1, TTAGGG repeat-binding factor 1, T-TRF1, TRF, TRF1 |
| Target Sequences: | NM_017489 NP_059523.2 P54274 |
Publications (1)
1
Eroded human telomeres are more prone to remain uncapped and to trigger a G2 checkpoint response. Jullien L, Mestre M, Roux P, Gire V. Nucleic acids research. 2013 41:900-11. (WB; Human)
[PubMed:23193277]
[PMC:PMC3553962]
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TRF1 / TERF1
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TRF1 / TERF1 Mouse anti-Human Monoclonal (BED5) Antibody
Human
ELISA, IHC, IHC-Fr, IHC-P
Unconjugated
50 µg/$460
TRF1 / TERF1 Mouse anti-Human Monoclonal (57-6) Antibody
Mouse, Rat, Primate, Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.1 ml/$460
TRF1 / TERF1 Mouse anti-Hamster Monoclonal (Biotin) (57-6) Antibody
Mouse, Rat, Hamster, Primate, Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
0.1 ml/$416
TRF1 / TERF1 Mouse anti-Hamster Monoclonal (DY650) (57-6) Antibody
Mouse, Rat, Hamster, Primate, Human
ELISA, IHC, IHC-P, WB
DY650 Conjugated
0.1 ml/$416
TRF1 / TERF1 Mouse anti-Hamster Monoclonal (DY488) (57-6) Antibody
Mouse, Rat, Hamster, Primate, Human
ELISA, IHC, IHC-P, WB
DY488 Conjugated
0.1 ml/$416
TRF1 / TERF1 Mouse anti-Hamster Monoclonal (DY550) (57-6) Antibody
Mouse, Rat, Hamster, Primate, Human
ELISA, IHC, IHC-P, WB
DY550 Conjugated
0.1 ml/$416
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$834
TRF1 / TERF1 Rabbit anti-Human Polyclonal (Leu215) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
TRF1 / TERF1 Rabbit anti-Human Polyclonal (aa260-439) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
Baculovirus
His
Less than 1.0 EU/µg protein (determined by LAL method).
50.5 kDa
50 µg/$721
TRF1 / TERF1 Mouse anti-Human Monoclonal (3H11) Antibody
Human
ELISA, IF, WB
Unconjugated
50 µl/$429
TRF1 / TERF1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
TRF1 / TERF1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
TRF1 / TERF1 Rabbit anti-Human Polyclonal (aa260-439) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
TRF1 / TERF1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
TRF1 / TERF1 Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
TRF1 / TERF1 Mouse anti-Human Monoclonal (BED5 #57-6) Antibody
Human
ELISA, WB
Unconjugated
200 µg/$516
TRF1 / TERF1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, WB
Unconjugated
40 µg/$485
TRF1 / TERF1 Rabbit anti-Human Polyclonal (aa70-120) Antibody
Human
ELISA, WB
Unconjugated
40 µg/$485
TRF1 / TERF1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$832
TRF1 / TERF1 Rabbit anti-Human Polyclonal (160-240 aa) Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
TRF1 / TERF1 Rabbit anti-Human Polyclonal (p219) Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
TRF1 / TERF1 Rabbit anti-Human Polyclonal (pSer219) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
TRF1 / TERF1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
TRF1 / TERF1 Mouse anti-Human Monoclonal (4E4) Antibody
Human
IF
Unconjugated
1 ml/$450
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