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Anti-TREX1 Antibody (Internal) LS-C82903

Ordering

Wt. Vol. Conc. Price
100 µg - 1 mg/ml $345
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular TREX1 Antibodies

Anti-TREX1 Antibody (Internal) LS-C82903
Rabbit Polyclonal to Human TREX1
Human, Mouse, Rat
IHC, Western blot, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human TREX1
Human, Mouse, Rat
IHC, Western blot, ELISA
Unconjugated

Details

Human TREX1
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC
  • Western blot (1 - 2 µg/ml)
  • ELISA

Specificity and Use

TREX1 antibody was raised against a 15 amino acid peptide near the center of human TREX1.
LS-E30632 - Liquid - 50 µg - $145.00
Internal
TREX1 antibody will not cross-react with the related protein TREX2.

Packaging

PBS containing 0.02% sodium azide
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
For research use only.

About TREX1

Q9NSU2 NM_016381 AAK07613.1

TREX1 Antibody, 3 repair exonuclease 1 Antibody, 3-5 exonuclease TREX1 Antibody, Aicardi-Goutieres syndrome 1 Antibody, AGS1 Antibody, CRV Antibody, Deoxyribonuclease III Antibody, DNase III Antibody, HERNS Antibody, DRN3 Antibody

Major cellular 3'-to-5' DNA exonuclease which digests single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) with mismatched 3' termini. Prevents cell-intrinsic initiation of autoimmunity. Acts by metabolizing DNA fragments from endogenous retroelements, including L1, LTR and SINE elements. Unless degraded, these DNA fragments accumulate in the cytosol and activate the IFN-stimulatory DNA (ISD) response and innate immune signaling.

Immunohistochemistry

Immunohistochemistry
Immunohistochemistry of TREX1 in human spleen tissue with TREX1 antibody at 2.5 ug/ml.

Immunofluorescence

Immunofluorescence
Immunofluorescence of TREX1 in Human Spleen cells with TREX1 antibody at 20 ug/ml.

Western blot

Western blot
Western blot of TREX1 in human spleen tissue lysate with TREX1 antibody at (A) 0.5 ug/ml and (B) 1 ug/ml
 

Requested From: United States
Date Requested: 12/2/2016

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