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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TREML1 / TLT1 Antibody (Extracellular Domain) LS‑C76524 Best Seller
Antibody
TLT1 antibody LS-C76524 is an unconjugated rat monoclonal antibody to mouse TLT1 (TREML1). Validated for ELISA and WB.
Catalog
Size
Price
LS-C76524-100
100 µg (0.5 mg/ml)
Unavailable

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Product Description

TLT1 antibody LS-C76524 is an unconjugated rat monoclonal antibody to mouse TLT1 (TREML1). Validated for ELISA and WB.
About TREML1 / TLT1
TREML1 / TLT1 is a member of the triggering receptor expressed on myeloid cells-like (TREM) family. The encoded protein is a type 1 single Ig domain orphan receptor localized to the alpha-granule membranes of platelets. The encoded protein is involved in platelet aggregation, inflammation, and cellular activation and has been linked to Gray platelet syndrome. Alternative splicing results in multiple transcript variants Q86YW5 Q86YW5

TREML1 Antibody, DJ238O23.3 Antibody, GLTL1825 Antibody, TLT-1 Antibody, Trem-like transcript 1 protein Antibody, TLT1 Antibody, PRO3438 Antibody


Specifications

Target
Mouse TREML1 / TLT1
Host
Rat
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG2b Monoclonal
Conjugations
Unconjugated. Also available conjugated with FITC.
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Western blot
  • ELISA
  • (applications tested for the base form of this product only)
Immunogen
TREML1 / TLT1 antibody was raised against nS0-derived rmTREML1 extracellular domain.
Epitope
Extracellular Domain
Specificity
Recognizes mouse TREML1. In direct ELISAs and Western Blots this antibody does not cross-react with rhTREML1.
Usage
Western Blot, Direct ELISA. Western Blot: This antibody can be used at 1-2 ug/mL with the appropriate secondary reagents to detect mouse TREML1. Using a colorimetric detection system, the detection limit for rmTREML1 is approximately 25 ng/lane under non-reducing conditions. Use of this antibody under reducing conditions is not recommended. Chemiluminescent detection will increase sensitivity by 5 to 50 fold. Direct ELISA: This antibody can be used at 0.5-1.0 ug/mL with the appropriate secondary reagents to detect mouse TREML1. The detection limit for rmTREML1 is approximately 1 ng/well.
Presentation
Lyophilized from PBS, 5% trehalose. Reconstitution: Reconstitute, sterile PBS. If 0.2 ml of PBS is used, the antibody concentration will be 500 ug/ml.
Reconstitution
PBS
Storage
Lyophilized powder may be stored at -20°C for short-term only. Aliquot and store at -20°C. Reconstituted product is stable for 1 year at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/21/2018

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