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Anti-TREM2 / TREM-2 Antibody (clone 78.18, FITC) LS-C188611

Ordering

Wt. Vol. Conc. Price
100 µg - 0.1 mg/ml $335
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular TREM2 / TREM-2 Antibodies

Anti-TREM2 / TREM-2 Antibody (aa199-212) IHC-plus™ LS-B2400
Goat Polyclonal to Human TREM2 / TREM-2
Human
IHC - Paraffin, ELISA
Unconjugated
Immunohistochemistry Image
Anti-TREM2 / TREM-2 Antibody (Extracellular Domain, clone 7H10-1) LS-C132650
Rat Monoclonal [clone 7H10-1] (IgG2b) to Mouse TREM2 / TREM-2
Mouse, Human
Western blot, Flow Cytometry, ELISA
Unconjugated
Anti-TREM2 / TREM-2 Antibody (aa19-168) LS-C150262
Sheep Polyclonal (IgG) to Mouse TREM2 / TREM-2
Mouse
ICC, Western blot
Unconjugated

100% Guaranteed 100% Guaranteed
Rat Monoclonal [clone 78.18] (IgG1) to Mouse TREM2 / TREM-2
Mouse
Flow Cytometry (applications tested for the base form of this product only)
FITC Conjugated

Details

Mouse TREM2 / TREM-2
Rat
Mouse (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [78.18]
Fluorescein. Also available Unconjugated or conjugated with RPE.
Protein G purified
Unmodified

Applications

  • Flow Cytometry
  • (applications tested for the base form of this product only)

Specificity and Use

TREM2 / TREM-2 antibody was raised against mouse TREM-2 Fc fusion protein.
Recognizes Triggering receptor expressed on myeloid cells 2 (TREM-2), an activating receptor of the Ig superfamily. TREM-2 forms a receptor signalling complex with DAP12 to trigger the activation of the immune response in macrophages and dendritic cells. It may be involved in chronic inflammation and may promote the production of constitutive rather than inflammatory chemokines and cytokines. TREM-2 may also have a functional role in osteoclast formation. Stimulation of TREM-2 with clone 78.18 enhances multinucleated osteoclast formation in vitro. Clone 78.18 may also be used to block TREM-2 on pre-osteoclasts to inhibit the formation of multinuclear osteoclasts and to inhibit bone resorption by mature osteoclasts.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

PBS, 0.09% sodium azide, 1% BSA
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles. Protect from light.
For research use only.

About TREM2 / TREM-2

Q9NZC2 NM_018965 NP_061838.1

TREM2 Antibody, Trem2b Antibody, TREM-2 Antibody, Trem2a Antibody, Trem2c Antibody

TREM2 / TREM-2 is a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL).

Flow Cytometry

Flow Cytometry
J774 cells stained with Rat anti-Mouse TREM2:FITC This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: United States
Date Requested: 12/2/2016

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