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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TRAIL‑R4 / DCR2 Antibody (N‑Terminus) LS‑C18136
DCR2 antibody LS-C18136 is an unconjugated rabbit polyclonal antibody to human DCR2 (TRAIL-R4). Validated for WB.
Antibody
Catalog
Size
Price
LS-C18136-50
50 µg
$345
LS-C18136-100
100 µg
$435

Popular TRAIL-R4 / DCR2 Products

Antibody
Species: Human
Applications: Flow Cytometry
Antibody
Species: Human
Applications: Flow Cytometry
Immunohistochemistry of DcR2 in mouse kidney node tissue with DcR2 antibody at 2.5 µg/ml.
Species: Human, Mouse, Rat
Applications: IHC, ICC, Immunofluorescence, Western blot
Antibody
Species: Human
Applications: Western blot, Flow Cytometry, ELISA

Product Description

DCR2 antibody LS-C18136 is an unconjugated rabbit polyclonal antibody to human DCR2 (TRAIL-R4). Validated for WB.

Specifications

Target
Human TRAIL-R4 / DCR2
Synonyms
TNFRSF10D, CD264, Decoy receptors 2, DCR2, TRAILR4, TRAIL-R4, TRUNDD, CD264 antigen, Decoy receptor 2, TRAIL receptor 4
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:250 - 1:500)
Immunogen
TRAIL-R4 / DCR2 antibody was raised against n terminus of the mature human TRAIL-R4 protein.
Epitope
N-Terminus
Specificity
Reacts with the N terminus of the mature human TRAIL-R4 protein.
Usage
Suitable for use in Western Blot. Western Blot: 1:250-1:500.
Presentation
PBS, pH 7.2, 0.01% Sodium Azide, 40% Glycerol
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About TRAIL-R4 / DCR2
Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL, and DcR1/TRID is a decoy receptor. Another member of the TRAIL receptor family was more recently identified and designated DcR2, TRAIL-R4, or TRUNDD. Q9UBN6 NM_003840 NP_003831.2


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Requested From: United States
Date Requested: 10/21/2018

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