• Antibodies
  • All Antibodies
  • Primary Antibodies
  • Secondary Antibodies
  • IHC-plus Antibodies
  • Isotype Control Antibodies
  • ELISA and Assay Kits
  • All Kits
  • Assay Kits
  • Traditional ELISA Kits
  • Cell-Based ELISA Kits
  • DNA-Binding ELISA Kits
  • Phospho-Specific ELISA Kits
  • ELISA Development Kits
  • Chemiluminescent CLIA Kits
  • Proteins
  • All Proteins
  • Recombinant Proteins
  • Native Proteins
  • Over-expression Lysates
  • Cell and Tissue Lysates
  • Bio-active Proteins
  • Animal-free Proteins
  • Synthetic Peptides
  • Biochemicals
  • All Biochemicals

  • Immunohistochemistry
  • Immunohistochemistry Reagents
  • Comprehensive IHC Reports
  • Custom IHC Services
  • TCR Screening Services
  • IHC-plus Antibodies
  • Immunohistochemistry Services

  • Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

  • TCR Screening Services

  • Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Have a question?
  • Purchasing
  • Product Ordering Terms and Conditions
  • Holiday Schedule
  • About the LSBio Guarantee
  • About Reviews
  • Reference Material
  • About LSBio (LifeSpan BioSciences Inc.)
  • About Our 2-million Specimen Tissue Bank
  • About Our IHC Validation Process
  • About Our IHC-plus™ Immunohistochemistry Protocol
  • Protocols
  • Secure Logins
  • Login to Our Secure ShareFile Site
  • Login to Our IHC Database
Contact Us

2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)
How to Buy - Details about how to buy our products. - To submit a new order. - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues. - To request technical information requests about an LSBio product or its application. - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login ▾
Wish List
View Cart

Anti-TRAIL-R3 / DCR1 Antibody (FITC) LS-C44963

Note: This antibody replaces LS-C58140
Catalog Size Price
LS-C44963-100 100 µg (0.1 mg/ml) Unavailable

Most Popular TRAIL-R3 / DCR1 Antibodies

Anti-TRAIL-R3 / DCR1 Antibody LS-C14814
Mouse Monoclonal (IgG1) to Human TRAIL-R3 / DCR1
ICC, Western blot, Flow Cytometry
Anti-TRAIL-R3 / DCR1 Antibody (aa33-63) LS-C83942
Goat Polyclonal to Human TRAIL-R3 / DCR1
IHC, ICC, Western blot, Flow Cytometry, ELISA
Anti-TRAIL-R3 / DCR1 Antibody (clone DJR3, PE) LS-C106229
Mouse Monoclonal [clone DJR3] (IgG1,k) to Human TRAIL-R3 / DCR1
Flow Cytometry
PE Conjugated
Flow Cytometry Image
Anti-TRAIL-R3 / DCR1 Antibody (aa1-280, clone TRAIL-R3-02) LS-C355225
Mouse Monoclonal [clone TRAIL-R3-02] (IgG1) to Human TRAIL-R3 / DCR1
Flow Cytometry
Anti-TRAIL-R3 / DCR1 Antibody (aa32-244) LS-C373895
Rabbit Polyclonal (IgG) to Human TRAIL-R3 / DCR1
Western blot
Western blot Image

100% Guaranteed
Mouse Monoclonal (IgG1) to Human TRAIL-R3 / DCR1
Immunoprecipitation, Flow Cytometry (applications tested for the base form of this product only)
FITC Conjugated


Human TRAIL-R3 / DCR1
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
Fluorescein. Also available conjugated with RPE.
Protein G purified


  • Immunoprecipitation
  • Flow Cytometry (1:1 - 1:10)
  • (applications tested for the base form of this product only)

Specificity and Use

TRAIL-R3 / DCR1 antibody was raised against dcR1-Fc Chimeric protein.
Recognizes human CD263, a 60 Kd cell surface protein, which is otherwise known as decoy receptor 1 (DcR1). CD263 is a member of the tumor necrosis factor (TNF) receptor superfamily that binds to TNF-related apoptosis inducing ligand (TRAIL). As the receptor does not possess cytoplasmic death domains it cannot induce apoptosis, but instead plays an important role in inhibiting TRAIL-induced apoptosis. CD263 is expressed in normal tissues including heart, skeletal tissues and peripheral blood neutrophils, but weakly expressed in tumor cells. The 2B8 antibody does not inhibit DcR1 (CD263) inhibitory function in TRAIL-induced apoptosis.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 1x10^6 cells in 100 ul. Method sheets are available on request.


PBS, pH 7.4, 0.09% sodium azide, 1% BSA.
For research use only.

About TRAIL-R3 / DCR1

O14798 NM_003841 NP_003832.2

TNFRSF10C Antibody, CD263 antigen Antibody, CD263 Antibody, Cytotoxic TRAIL receptor-3 Antibody, Decoy receptor 1 Antibody, DCR1 Antibody, DCR1-TNFR Antibody, LIT Antibody, Lymphocyte inhibitor of TRAIL Antibody, TRAIL-R3 Antibody, TRAILR3 Antibody, TRAIL receptor 3 Antibody, TRID Antibody

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL. Two decoy receptors for TRAIL have been identified and designated DcR1/TRID/TRAIL-R3/LIT and DcR2/TRAIL-R4/TRUNDD.

Flow Cytometry

Flow Cytometry
Human Granulocytes stained with Mouse anti-Human CD263 (LS-C44964). This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: 
Date Requested: 3/22/2018

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2018 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy

Catalog Number